Results 31 to 40 of about 1,411 (168)

Fournier gangrene [PDF]

Clinical Case Reports, 2015
Key Clinical MessageFournier gangrene is a rapidly progressive necrotizing infection of the perineal and genital fascia, often polymicrobial. Severity is increased in older patients, diabetics and the immunocompromised. As in this case, the disease can have an indolent onset. Early recognition and aggressive treatment is important.
openaire   +2 more sources

Safety outcomes of antidiabetic medications: A comprehensive review of the EU summaries of product characteristics and international clinical practice guidelines

British Journal of Clinical Pharmacology, EarlyView.
Aims Information on the safety profile of antidiabetic medications is essential for informed treatment decisions in type 2 diabetes mellitus. Although this information is available in regulatory documents of individual drugs, a comprehensive overview across all approved antidiabetics is lacking.
David Liang, Daniala L. Weir, Safana Thevasahayam, Vera H. M. Deneer, Arno Siebes, Helga Gardarsdottir   +5 more
wiley   +1 more source

Efficacy of Non-invasive Serum Markers in Predicting the Prognosis of Fournier Gangrene

Journal of Urological Surgery
Objective: Fournier gangrene is a true urological emergency. This study aimed to evaluate the efficacy of biochemical diagnostic markers in predicting the prognosis of patients who presented to the hospital with Fournier gangrene. Materials and Methods:
Özer Güzel, Ahmet Asfuroğlu, Yılmaz Aslan, Melih Balcı, Şeref Coşer   +4 more
doaj   +1 more source

Fournier′s gangrene of the penis

Indian Journal of Plastic Surgery, 2005
Fournier′s gangrene is a rare, fulminant, though generally localized disease of the scrotum and penis with occasional extension up the abdominal wall. The usual organism is an anaerobic streptococcus synergistic with some second organism.
Francis Leo Tauro, M Roshan, B S Sathish Rao, J Ravikrishnan, Leo T Menezes   +4 more
doaj   +1 more source

Fournier’s Gangrene: 10-Year Experience of a Plastic Surgery and Burns Department at a Tertiary Hospital

Acta Médica Portuguesa, 2019
Introduction: Fournier gangrene is a polymicrobial life threatening infection of perineal subcutaneous soft tissues with its point of origin in urologic, colorectal or skin diseases.
João Mendes Louro, Miguel Albano, João Baltazar, Miguel Vaz, Carla Diogo, Sara Ramos, Luís Cabral   +6 more
doaj   +1 more source

Prevalence and Characteristics of Urinary Catheter Blockage in Patients With Long‐Term Urinary Catheterization: A Cross‐Sectional Study

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aims To determine the prevalence and characteristics of urinary catheter blockage in older patients using objective indicators and to characterize obstructive materials and microbiota. Design A cross‐sectional study. Methods Patients aged ≥ 65 years with an indwelling catheter for ≥ 24 h were recruited from a long‐term care hospital.
Natsumi Hirose, Mao Kunimitsu, Chihiro Takizawa, Yukie Kataoka, Minami Shinkawa, Chika Takada, Atsuo Kawamoto, Jun Kamei, Haruki Kume, Chizuko Konya, Hiromi Sanada, Gojiro Nakagami   +11 more
wiley   +1 more source

Tirzepatide and SGLT2 Inhibitors for Heart Failure With Preserved Ejection Fraction and Obesity: Entering a New Cardiometabolic Therapeutic Era

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Tirzepatide and SGLT2 inhibitors act through distinct but complementary mechanisms in obesity‐related HFpEF: tirzepatide targets adiposity, inflammation, and insulin resistance, while SGLT2 inhibitors improve decongestion, myocardial energetics, and cardiac remodeling.
Zakariye Isak Mohamed, Abdinasir Adam Shidane, Abdullahi Mohamud Abdiasis, Mohamed Hassan Hussein, Ayaanle Osman Ibrahim, Anas Ali Abdi, Kowthar Ismail Hashi, Mohamed Abdullahi Mohamud, Ali Jimale Mohamed   +8 more
wiley   +1 more source

PREDISPOSITION FACTORS ANALYSIS FOR FOURNIER'S GANGRENE DEFECTS CLOSURE COMPLICATION

Jurnal Rekonstruksi dan Estetik, 2020
Highlights: • Fournier's gangrene remains a serious condition with a relatively high mortality rate. • Early identification of predisposing factors, combined with invasive and aggressive treatment approaches, is crucial in mitigating morbidity ...
Bayu Fasi Bermani, Sitti Rizaliyana, Ira Handriani   +2 more
doaj   +1 more source

Effect of Endophytic Fungi on Thrips tabaci Development and Population Dynamics

Journal of Applied Entomology, Volume 150, Issue 8, Page 1102-1114, September 2026.
ABSTRACT Endophytic fungi are promising biocontrol agents because they colonise healthy plant tissues asymptomatically while inducing systemic resistance that negatively affects herbivorous insects. We investigated whether treatments with the endophytes Trichoderma harzianum and Beauveria bassiana in two onion cultivars (Allium cepa L.; Sturon and Red ...
Ngoc Anh Vu, Sevgan Subramanian, Rainer Meyhöfer   +2 more
wiley   +1 more source

Goniothalamin as a Styryl‐Lactone Toxicophore in Cancer Models: Electrophile‐Driven DNA Damage, Reactive Oxygen Species–Endoplasmic Reticulum Stress Signaling and Detoxification‐Relevant Safety Considerations

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Goniothalamin (GTN) exerts anticancer effects by promoting reactive oxygen species (ROS) generation, glutathione (GSH) depletion, DNA damage, endoplasmic reticulum (ER) stress, and mitochondrial dysfunction. These interconnected events trigger apoptosis, necroptosis, anoikis, and autophagy, while modulating mitogen‐activated protein kinase (MAPK ...
Nataša Joković, Strahinja Pešić, Marija Novaković, Anđela Dubroja Krstić, William N. Setzer, Javad Sharifi‐Rad, Daniela Calina   +6 more
wiley   +1 more source