Results 51 to 60 of about 244,928 (249)

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

Language design for a personal learning environment design language [PDF]

, 2008
Approaching technology-enhanced learning from the perspective of a learner, we foster the idea of learning environment design, learner interactions, and tool interoperability.
Mödritscher, Felix, Sigurdarson, Steinn, Wild, Fridolin   +2 more
core   +3 more sources

Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation

Advanced Science, EarlyView.
FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin, Aini Pan, Zhuoning Miao, Yanyan Zhao, Xianan Mo, Heng Sun, Chunmei Fan, Junyu Guo, Bingbing Wu, Weiliang Shen, Qiangqiang Zheng, Jun Lu, Xi Jiang, Zi Yin, Xiao Chen   +14 more
wiley   +1 more source

The ModelCC Model-Driven Parser Generator

, 2015
Syntax-directed translation tools require the specification of a language by means of a formal grammar. This grammar must conform to the specific requirements of the parser generator to be used.
Berzal, Fernando, Cortijo, Francisco J., Cubero, Juan-Carlos, Quesada, Luis   +3 more
core   +2 more sources

Subvoxel Control of Fiber Orientation via Multidirectional Shearing in 3D Printing

Advanced Science, EarlyView.
A novel 3D printing technique enables subvoxel control of fiber orientation in all three directions through multidirectional shearing using nozzle rotation and inclination. It allows localized and tunable mechanical and thermal responses through programmable microstructures within a strand.
Berin Šeta, Marco Brander, Michael Sandberg, Md. Tusher Mollah, Vipin Kumar, Jon Spangenberg   +5 more
wiley   +1 more source

Region-based memory management for Mercury programs

, 2012
Region-based memory management (RBMM) is a form of compile time memory management, well-known from the functional programming world. In this paper we describe our work on implementing RBMM for the logic programming language Mercury. One interesting point
Janssens, Gerda, Phan, Quan, Somogyi, Zoltan   +2 more
core   +1 more source

Systematic Benchmarking of a Noise‐Tolerant Conductive Hydrogel Electrode for Epidermal Bioelectronics

Advanced Science, EarlyView.
General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen, Ioannis Ziogas, Shirina Alsaedi, Mouza Alshehhi, Shahd Almheiri, Adil Rehman, Khulood Al Shehhi, Hani Saleh, Ahsan Khandoker, Charalampos Pitsalidis, Antoun Khawaja, Anna‐Maria Pappa   +11 more
wiley   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

A Framework for Evaluating Model-Driven Self-adaptive Software Systems [PDF]

, 2019
In the last few years, Model Driven Development (MDD), Component-based Software Development (CBSD), and context-oriented software have become interesting alternatives for the design and construction of self-adaptive software systems.
Magableh, Basel
core   +2 more sources

A Large-Scale Study on the Usage of Testing Patterns that Address Maintainability Attributes (Patterns for Ease of Modification, Diagnoses, and Comprehension)

, 2017
Test case maintainability is an important concern, especially in open source and distributed development environments where projects typically have high contributor turnover with varying backgrounds and experience, and where code ownership changes often.
Gonzalez, Danielle, Mirakhorli, Mehdi, Nagappan, Mei, Popovich, Andrew, Santos, Joanna C. S.   +4 more
core   +1 more source