Results 61 to 70 of about 457,330 (266)
Advanced Science, EarlyView.Nonsyndromic orofacial clefts (NSOFCs) are the most common craniofacial defects. Exome sequencing of 214 sporadic cases sheds new light on its genetic architecture and identifies many candidate pathogenic variants. Furthermore, functional studies establish BOC as a novel causal gene and reveal an unusual two‐locus model of inheritance via the epistatic
Qing He +16 more
wiley +1 more source
EBG: A Lazy Functional Programming Language Implemented on the Java Virtual Machine [PDF]
arXiv, 2018 This technical report describes the implementation of a lazy functional programming language on the Java VM.
arxiv
On the Evolution of Programming Languages [PDF]
arXiv, 2020 This paper attempts to connects the evolution of computer languages with the evolution of life, where the later has been dictated by \emph{theory of evolution of species}, and tries to give supportive evidence that the new languages are more robust than the previous, carry-over the mixed features of older languages, such that strong features gets added
arxiv
Advanced Science, EarlyView.These findings elucidate the innovative role of HIC1 as a transcriptional activator in GC, driving the initiation of pyroptosis and enhancing CD8+ T cell infiltration, which has certain novelty and creative significance. Collectively, targeting HIC1 can present an appealing immunotherapeutic strategy to improve outcomes in GC patients.
Mengjie Kang +4 more
wiley +1 more source
Purely Functional Structured Programming [PDF]
arXiv, 2010 The idea of functional programming has played a big role in shaping today's landscape of mainstream programming languages. Another concept that dominates the current programming style is Dijkstra's structured programming. Both concepts have been successfully married, for example in the programming language Scala. This paper proposes how the same can be
arxiv
Autonomous Self‐Evolving Research on Biomedical Data: The DREAM Paradigm
Advanced Science, EarlyView.DREAM is a fully autonomous, self‐evolving biomedical research system capable of independently formulating scientific questions, performing analyses, and making new discoveries without human intervention. Validated in biomedical studies, DREAM significantly outperforms human scientists in research efficiency, accelerating scientific discovery and ...
Luojia Deng +3 more
wiley +1 more source
The impact of fourth generation computers on NASTRAN [PDF]
, 1975 The impact of 'fourth generation' computers (STAR 100 or ILLIAC 4) on NASTRAN is considered.
Rogers, J. L., Jr.
core +1 more source
Advanced Science, EarlyView.Colloidal nanoparticles self‐assembly advances towards intelligent, customized assembly through precise control of binary co‐assemblies. This review explores the evolution from monolithic to binary assemblies, highlighting how the AI‐guided programmable assembly approach has the potential to shift from passive assembly to active intelligent design.
Cancan Li +5 more
wiley +1 more source
Transpiling Programmable Computable Functions to Answer Set Programs [PDF]
arXiv, 2018 Programming Computable Functions (PCF) is a simplified programming language which provides the theoretical basis of modern functional programming languages. Answer set programming (ASP) is a programming paradigm focused on solving search problems. In this paper we provide a translation from PCF to ASP.
arxiv
Blockchain‐Empowered H‐CPS Architecture for Smart Agriculture
Advanced Science, EarlyView.This article reviews the current system architectures for smart agriculture and proposes a blockchain‐empowered hierarchical cyber‐physical system (H‐CPS) framework. It discusses the challenges and outlines future research directions, including the use of semantic blockchain to handle complex data and models.
Xiaoding Wang +8 more
wiley +1 more source