Results 41 to 50 of about 12,171,095 (269)

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Oscillation Criteria of Fourth-Order Differential Equations with Delay Terms

Journal of Function Spaces, 2022
The aim of this paper is to derive oscillation criteria of the following fourth-order differential equation with delay term rxz′′′xγ′+∑i=1nqixfzηix=0, under the assumption ∫x0∞r−1/γsds=∞. The results are based on comparison with the oscillatory behaviour
Shoura Ahmed Balatta, Ishak Hashim, Ahmad Sami Bataineh, Eddie Shahril Ismail   +3 more
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

High-Order, Accurate Finite Difference Schemes for Fourth-Order Differential Equations

Axioms
This article is devoted to the study of high-order, accurate difference schemes’ numerical solutions of local and non-local problems for ordinary differential equations of the fourth order. Local and non-local problems for ordinary differential equations
Allaberen Ashyralyev, Ibrahim Mohammed Ibrahım   +1 more
doaj   +1 more source

Oscillation of fourth-order strongly noncanonical differential equations with delay argument

Advances in Difference Equations, 2019
The aim of this paper is to study oscillatory properties of the fourth-order strongly noncanonical equation of the form (r3(t)(r2(t)(r1(t)y′(t))′)′)′+p(t)y(τ(t))=0, $$ \bigl(r_{3}(t) \bigl(r_{2}(t) \bigl(r_{1}(t)y'(t) \bigr)' \bigr)' \bigr)'+p(t)y \bigl(
B. Baculikova, J. Dzurina
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Backward difference replacements of the space derivative in first order hyperbolic equations [PDF]

, 1983
Two families of two-time level difference schemes are developed for the numerical solution of first order hyperbolic partial differential equations with one space variable.
Khaliq, AQM, Twizell, EH
core   +4 more sources

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Nonlinear Differential Equations and Dynamical Systems [PDF]

, 2021
This Special Edition contains new results on Differential and Integral Equations and Systems, covering higher-order Initial and Boundary Value Problems, fractional differential and integral equations and applications, non-local optimal control, inverse ...

core   +1 more source