A patient‐specific, imaging‐guided aid enables precise and reproducible drug delivery to the inner ear. By guiding therapeutic agents directly to the round window niche, this approach reduces variability in drug localization, improves delivery safety, and addresses a critical bottleneck in inner ear therapy, offering a scalable strategy for precision ...
Yanjing Luo +4 more
wiley +1 more source
Integrative Proteomics and Machine Learning Identify SLC27A2 as a Candidate Biomarker and Potential Mediator of Pyrotinib Response in HER2-Positive Breast Cancer. [PDF]
Zhang S +7 more
europepmc +1 more source
Microneedles Mediated Delivery of Nanodiamonds for Quantum Sensing of Free Radicals in Skin Tissue
Fluorescent nanodiamonds are nanoscale sensors capable of monitoring cellular stress responses. However, to function effectively, they must be delivered into cells or tissues. Here, we demonstrate their application in the skin by developing a dissolvable microneedle platform that dissolves after skin insertion, enabling the delivery of nanodiamonds ...
Siyu Fan +10 more
wiley +1 more source
Minimally Invasive Treatment of Die-Punch Fractures and Related X-Ray Parameters. [PDF]
Hu J +5 more
europepmc +1 more source
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le +4 more
wiley +1 more source
A novel two-parameter discrete exponentiated exponential distribution with its neutrosophic extension: mathematical characterization and real-world count data modeling. [PDF]
P FA, V S.
europepmc +1 more source
Microstructures fabricated by two‐beam DLIP combining spatial‐period and roughness gradients are fabricated to enhance directional transport of water droplets. The coupled gradients increase transport distance by 160% and strongly suppress motion against the gradient, demonstrating an effective strategy for controlled droplet manipulation.
Tianhao Wu +3 more
wiley +1 more source
Comparative Analysis of Twenty Intraocular Lens Power Calculation Formulas in Medium-Long Eyes. [PDF]
Stopyra W +2 more
europepmc +1 more source
EEG and gut microbiota response patterns in high-altitude indigenous populations. [PDF]
Bai K +19 more
europepmc +1 more source
Identifying populations with faster cognitive decline using blood-based biomarkers. [PDF]
Pike JR +17 more
europepmc +1 more source

