Results 31 to 40 of about 326,856 (211)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
On the Mean Values of Certain Character Sums
Abstract and Applied Analysis, 2013 Let q≥5 be an odd number. In this paper, we study the fourth power mean of certain character sums ∑χmodq,χ-1=-1*∑1≤a≤q/4aχa4 and ∑χmodq,χ-1=1*∑1≤a≤q/4aχa4, where ∑* denotes the summation over primitive characters modulo q, and give some asymptotic ...
Zhefeng Xu, Huaning Liu
doaj +1 more source
Energy Reports, 2022 Wind power provides a clean and feasible solution to generate electricity. The development of wind power applications requires a deep analysis of wind profiles and an accurate prediction of wind energy at a study site. This work explores the distribution
Husain R. Alsamamra +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
ElectricaThis article proposes the effectiveness of a Dynamic Voltage Restorer (DVR) based on Quantum Calculus-based Least Mean Fourth (q-LMF) for compensating the impact of grid voltage perturbation.
Prashant Kumar, Sabha Raj Arya
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
New Mixed Exponential Sums and Their Application
Journal of Applied Mathematics, 2014 The main purpose of this paper is to introduce a new mixed exponential sums and then use the analytic methods and the properties of Gauss sums to study the computational problems of the mean value involving these sums and give an interesting ...
Yu Zhan, Xiaoxue Li
doaj +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source