Results 51 to 60 of about 373,020 (318)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Surveillance of Highly Pathogenic Avian Influenza Virus in Wild Canids from Pennsylvania, USA

open access: yesAnimals
The avian influenza virus is a global pathogen with significant health and economic implications. While primarily a pathogen of wild and domestic birds, recent outbreaks of the H5N1 highly pathogenic avian influenza virus (HPAIV) clade 2.3.4.4b have ...
Kevin D. Niedringhaus   +13 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Fur Farming: EU Citizens’ Stance

open access: yesSci
Despite its economic profitability, fur farming in Europe, responsible for half of global production, faces a growing ethical backlash. Animal welfare concerns, particularly regarding mink, foxes, and raccoon dogs kept in restrictive cages, have ...
Fernando Mata   +3 more
doaj   +1 more source

Update on oral vaccination of foxes and raccoon dogs against rabies

open access: yesEFSA Journal, 2015
An assessment of a report issued by the European Commission in 2002 is presented about the oral vaccination of foxes against rabies, as well as additional topics such as the rabies aetiology and its occurrence in Europe, the target species for oral ...
Animal Health and Welfare (AHAW)
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Damage from predation on the reindeer husbandry area in Finland during the years 1976-83

open access: yesRangifer, 1985
During the years 1976-1983 predators killed a total of 8900 reindeer in Finland. The highest numbers of reindeer killed by predators were found in the marked areas of Inari, Kuusamo and Sodankyla and in the reindeer herding areas of Kasivarsi (a total of
Mauri Nieminen, Juhani Leppäluoto
doaj   +1 more source

Species composition of Trichinella in domestic and wild animals in Bulgaria [PDF]

open access: yesBulgarian Journal of Veterinary Medicine, 2019
Four Trichinella species cause trichinellosis in Europe: Trichinella spiralis, Trichinella britovi, Trichinella nativа and Trichinella pseudospiralis. The aim of our study was to determine the prepon-derance of Trichinella species in Bulgaria.
N. Lalkovski
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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