Results 131 to 140 of about 19,594 (220)

The reduction in FOXA2 activity during lung development in fetuses from diabetic rat mothers is reversed by Akt inhibition

FEBS Open Bio, 2018
Hyperglycemia during pregnancy is associated with fetal lung development disorders and surfactant protein (SP) deficiency. Here, we examined the role of FOXA2 and Akt signaling in fetal lung development during diabetic pregnancy. Sprague‐Dawley rats were
Qingmiao Zhang, Xinqun Chai, Feitao Deng, Weixiang Ouyang, Ting Song   +4 more
doaj   +1 more source

Genome-wide roles of Foxa2 in directing liver specification [PDF]

Journal of Molecular Cell Biology, 2012
Chenhuan, Xu, Xiaowen, Lu, Eric Z, Chen, Zhiying, He, Borjigin, Uyunbilig, Guangpeng, Li, Yue, Ma, Lijian, Hui, Bin, Xie, Yuan, Gao, Xiaoyan, Ding, Yiping, Hu, Ping, Hu, Jing-Dong J, Han, Xin, Wang   +14 more
openaire   +2 more sources

Scaffolding for human pluripotent stem cell lineage specification [PDF]

, 2013
Current research regarding stem cells is the premise behind this project. These cells have the potential to develop into any kind of cell in the human body.
Dai, Thanh
core   +1 more source

FOXA2 rewires AP-1 for transcriptional reprogramming and lineage plasticity in prostate cancer

Nature Communications
FOXA family proteins act as pioneer factors by remodeling compact chromatin structures. FOXA1 is crucial for the chromatin binding of the androgen receptor (AR) in both normal prostate epithelial cells and the luminal subtype of prostate cancer (PCa ...
Zifeng Wang, Scott L. Townley, Songqi Zhang, Mingyu Liu, Muqing Li, Maryam Labaf, Susan Patalano, Kavita Venkataramani, Kellee R. Siegfried, Jill A. Macoska, Dong Han, Shuai Gao, Gail P. Risbridger, Renea A. Taylor, Mitchell G. Lawrence, Housheng Hansen He, Luke A. Selth, Changmeng Cai   +17 more
doaj   +1 more source

FXR controls insulin content by regulating Foxa2-mediated insulin transcription

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Farnesoid X receptor (FXR) is a nuclear ligand-activated receptor of bile acids that plays a role in the modulation of insulin content. However, the underlying molecular mechanisms remain unclear. Forkhead box a2 (Foxa2) is an important nuclear transcription factor in pancreatic β-cells and is involved in β-cell function.
Dan, Yan, Moyang, Lv, Xiangchen, Kong, Linxian, Feng, Ying, Ying, Wenjuan, Liu, Xin, Wang, Xiaosong, Ma   +7 more
openaire   +2 more sources

Forkhead box A2 (FOXA2) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

MHC matching improves engraftment of iPSC-derived neurons in non-human primates [PDF]

, 2017
et al,, Glasser, Matthew F
core   +2 more sources

Foxa1 and Foxa2 in the intervertebral disk

Developmental Biology, 2011
Maier, Jennifer, Lo, Yin Ting, Harfe, Brian   +2 more
openaire   +1 more source

FOXA2 promotes prostate cancer growth in the bone.

American journal of translational research
Bone metastasis frequently occurs in advanced-stage prostate cancer (PCa) patients. Understanding the mechanisms that promote PCa-mediated bone destruction is important for the identification of therapeutic targets against this lethal disease. We found that forkhead box A2 (FOXA2) is expressed in a subset of PCa bone metastasis specimens.
Zachary M, Connelly, Renjie, Jin, Jianghong, Zhang, Shu, Yang, Siyuan, Cheng, Mingxia, Shi, Justin Mm, Cates, Runhua, Shi, David J, DeGraff, Peter S, Nelson, Yunlong, Liu, Colm, Morrissey, Eva, Corey, Xiuping, Yu   +13 more
openaire   +1 more source

Live imaging and functional characterization of the avian hypoblast redefine the mechanisms of primitive streak induction. [PDF]

Nat Commun
Villedieu A, Alegria-Prévot O, Phan C, Ieda Y, Corson F, Gros J.   +5 more
europepmc   +2 more sources