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FOXP3 (in)stability and cancer immunotherapy
CytokineDysregulation of regulatory T cells (Tregs) is described in the context of inflammatory and autoimmune diseases, and cancer. Forkhead box P3 (FOXP3) is a transcription factor that its activity is an indicator of Treg identity. FOXP3 induces metabolic versatility in intra-tumoral Tregs, so that its deficiency mediates Treg instability or even gives rise
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Two FOXP3+CD4+ T cell subpopulations distinctly control the prognosis of colorectal cancers
Nature Network Boston, 2016Takuro Saito+21 more
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Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis
Nature Network Boston, 2013N. Komatsu+8 more
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FOXP3+T cell subset characterized by Helios, FOXP3 and CD45RO in patients with melanoma
Journal of Dermatological Science, 2013Takashi Nomura+3 more
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Rescue of Foxp3 Deficiency by Inducible Activation of a Bicistronic Foxp3/EGFP Allele
Journal of Allergy and Clinical Immunology, 2006Calvin B. Williams+4 more
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