Results 91 to 100 of about 3,443,174 (389)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

A Data-Based Hybrid Chemistry Acceleration Framework for the Low-Temperature Oxidation of Complex Fuels

Energies
The oxidation of complex hydrocarbons is a computationally expensive process involving detailed mechanisms with hundreds of chemical species and thousands of reactions.
Sultan Alqahtani, Kevin M. Gitushi, Tarek Echekki   +2 more
doaj   +1 more source

Quantifying pollution transport from the Asian monsoon anticyclone into the lower stratosphere [PDF]

Atmospheric Chemistry and Physics, 2017
Pollution transport from the surface to the stratosphere within the Asian monsoon circulation may cause harmful effects on stratospheric chemistry and climate.
F. Ploeger, P. Konopka, K. Walker, M. Riese   +3 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Lung surface-active fraction as a model system for macromolecular ultrastructural studies with Crotalus atrox venom

Journal of Lipid Research, 1973
The dog lung surface-active fraction and phosphatidylcholine constituents were subjected to hydrolysis by Crotalus atrox phospholipase A2. Relative rates of hydrolysis were: dipalmitoyl glycerophosphorylcholine > phosphatidylcholine isolated from the ...
M.F. Frosolono, R. Pawlowski, B.L. Charms, C. Corbusier, M. Abrams, J. Jones, III   +5 more
doaj   +1 more source

Improved decision making with similarity based machine learning: applications in chemistry

Machine Learning: Science and Technology, 2023
Despite the fundamental progress in autonomous molecular and materials discovery, data scarcity throughout chemical compound space still severely hampers the use of modern ready-made machine learning models as they rely heavily on the paradigm, ‘the ...
Dominik Lemm, Guido Falk von Rudorff, O Anatole von Lilienfeld   +2 more
doaj   +1 more source

Enhanced cosmic-ray flux toward zeta Persei inferred from laboratory study of H3+ - e- recombination rate

, 2003
The H3+ molecular ion plays a fundamental role in interstellar chemistry, as it initiates a network of chemical reactions that produce many interstellar molecules. In dense clouds, the H3+ abundance is understood using a simple chemical model, from which
A. Al-Khalili, A. Ehlerding, A. J. Huneycutt, A. Neau, AE Orel, B. J. McCall, BD Savage, BJ McCall, BJ McCall, BJ McCall, CM Lindsay, D Strasser, E Herbst, EF van Dishoeck, F. Hellberg, F. Österdahl, G Sundström, G. H. Dunn, H Kreckel, IF Schneider, J. Semaniak, JA Cardelli, JB Paul, M Larsson, M. Larsson, MJ Jensen, N. Djuric, O. Novotny, R Plasil, R. J. Saykally, R. Thomas, RC Bohlin, S Lepp, S. Kalhori, SL Guberman, T Tanabe, T. R. Geballe, TR Geballe, TR Geballe, V Kokoouline, WD Watson   +40 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

In situ measurements of tropospheric volcanic plumes in Ecuador and Colombia during TC^4 [PDF]

, 2011
A NASA DC-8 research aircraft penetrated tropospheric gas and aerosol plumes sourced from active volcanoes in Ecuador and Colombia during the Tropical Composition, Cloud and Climate Coupling (TC^4) mission in July–August 2007. The likely source volcanoes
Anderson, B. E., Browell, E. V., Carn, S. A., Crounse, J., Dibb, J. E., Diskin, G., Froyd, K. D., Hair, J. W., Krotkov, N. A., Sachse, G., Spencer, K., Vay, S. A., Wennberg, P.   +12 more
core   +2 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source