Results 221 to 230 of about 3,443,174 (389)

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Correction: Antibodies and cryptographic hash functions: quantifying the specificity paradox. [PDF]

Front Immunol
Petrella RJ.
europepmc   +1 more source

ISOLATION OF COMPOUNDS FROM DRAC FRACTION OF THE ACETONE ROOT EXTRACT OF DICHAPETALUM MADAGASCARIENSE UNIVERSITY OF GHANA DEPARTMENT OF CHEMISTRY

Adu-Poku, George
openalex   +1 more source

Perturbing phytoplankton: response and isotopic fractionation with changing carbonate chemistry in two coccolithophore species

, 2010
Rosalind E. M. Rickaby, Jorijntje Henderiks, Jodi N. Young   +2 more
openalex   +1 more source

On the ionisation fraction in protoplanetary disks III. The effect of X-ray flares on gas-phase chemistry [PDF]

, 2006
M. Ilgner, Richard P. Nelson
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

From experimental data to thermophysical insight: characterizing choline-based ionic liquids using advanced data analysis. [PDF]

RSC Adv
Souvenir-Zafindrajaona MS, Mbakidi JP, Wagner Z, Bouquillon S, Bendová M.   +4 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Rosa sp and Hibiscus sabdariffa L Extract in Ethanol Fraction as Acid Base Indicator: Application of Green Chemistry in Education

, 2019
Nur Tsalits Fahman Mughni
openalex   +2 more sources

Identifying and Mitigating Adverse X‑ray Induced Effects in Operando Spectroscopic Studies of Copper Exchanged Zeolites. [PDF]

J Phys Chem C Nanomater Interfaces
Wieser J, Newton MA, Rzepka P, Leidinger PM, Ramakrishnan M, Just J, van Bokhoven JA.   +6 more
europepmc   +1 more source