Results 41 to 50 of about 1,040,831 (304)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Cloud, precipitation and radiation responses to large perturbations in global dimethyl sulfide [PDF]
Atmospheric Chemistry and Physics, 2018 Natural aerosol emission represents one of the largest uncertainties in our understanding of the radiation budget. Sulfur emitted by marine organisms, as dimethyl sulfide (DMS), constitutes one-fifth of the global sulfur budget and yet the ...
S. L. Fiddes +6 more
doaj +1 more source
Imaging of fuel mixture fraction oscillations in a driven system using acetone PLIF [PDF]
, 2004 Measurements of fuel mixture fraction are made for a jet flame in an acoustic chamber. Acoustic forcing creates a spatially-uniform, temporally-varying pressure field which results in oscillatory behavior in the flame .
Culick, F. E. C. +3 more
core
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phenylpropanoid-enriched broccoli seedling extract can reduce inflammatory markers and pain behavior
Journal of Translational Medicine, 2023 Background Pain is a worldwide problem requiring an effective, affordable, non-addictive therapy. Using the edible plant broccoli, a growth protocol was developed to induce a concentrated combinatorial of potential anti-inflammatories in seedlings ...
Aleksandra A. Gurgul +6 more
doaj +1 more source
Hybrid RANS/PDF calculations of sydney swirling flames [PDF]
, 2009 In this work, we perform steady 2D axisymmetric RANS and hybrid RANS/PDF calculations to predict the turbulent flow and mixing fields of swirling inert flows and flames.
De Meester, Reni +2 more
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Nitrogen fractionation in ammonia and its insights on nitrogen chemistry [PDF]
, 2023 E. Redaelli +3 more
openalex +1 more source