Results 91 to 100 of about 26,243 (274)

A novel approach to design and analyze fractional order PID controller for speed control of brushless DC motor

Renewable Energy and Sustainable Development
In industries Brushless DC(BLDC) motors with conventional PID controllers which are based on linear control theory are widely used.  BLDC motors often require precise speed control for various applications like robotics, electric vehicles and industrial ...
Megha Sharma, Shailly Sharma, Jayashri Vajpai   +2 more
doaj   +1 more source

IMPLEMENTATION OF NONLINEAR FUZZY LOGIC FRACTIONAL ORDER PID CONTROLLER (NFL-FOPID) WITH FIRST ORDER TRANSFER FUNCTION

ICTACT Journal on Soft Computing, 2018
Today, the requirement of controllers in the field of engineering and process industries is going to be increased in order to control. Among all controllers, Proportional Integral Derivative (PID) controllers are widely used due to its easy ...
U. Hada, V. Soni
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Fractional Order Fuzzy Control of Nuclear Reactor Power with Thermal-Hydraulic Effects in the Presence of Random Network Induced Delay and Sensor Noise having Long Range Dependence

, 2013
Nonlinear state space modeling of a nuclear reactor has been done for the purpose of controlling its global power in load following mode. The nonlinear state space model has been linearized at different percentage of reactor powers and a novel fractional
Das, Saptarshi, Das, Shantanu, Pan, Indranil   +2 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Earthquake-Resilient Structural Control Using PSO-Based Fractional Order Controllers

Fractal and Fractional
Seismic-induced vibration mitigation in multi-degree-of-freedom (MDOF) building structures calls for efficient and adaptive control strategies. Fractional-order PIλDμ controllers allow increased flexibility in tuning when compared with the conventional ...
Sanoj Kumar, Harendra Pal Singh, Musrrat Ali, Abdul Rahaman Wahab Sait   +3 more
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Research on TID Controller Design for Fractional-Order Time-Delay Systems

Applied Sciences
Fractional-order time-delay systems boast better dynamic performance than integer-order ones in optimally controlling industrial design objects. However, in lack of commendable methodologies, designing proper controllers for these systems confronts a ...
Jinyuan Zhang, Ling Zhang, Zhisheng Liang, Rongnian Tang   +3 more
doaj   +1 more source