Results 121 to 130 of about 1,550,178 (378)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Back to Basics: Meaning of the Parameters of Fractional Order PID Controllers

open access: yesMathematics, 2019
The beauty of the proportional-integral-derivative (PID) algorithm for feedback control is its simplicity and efficiency. Those are the main reasons why PID controller is the most common form of feedback.
Inés Tejado   +4 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

The Floquet-Lyapunov transformation for fractional discrete-time linear systems with periodic parameters [PDF]

open access: yesArchives of Control Sciences
The Floquet-Lyapunov transformation is extended to fractional discrete-time linear systems with periodic parameters. A procedure for computation of the transformation is proposed and illustrated by a numerical example.
Tadeusz Kaczorek, Andrzej Ruszewski
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

On a unique solution of fractional differential system

open access: yesTikrit Journal of Pure Science, 2019
The aim of the study is to investigate the existence and uniqueness of solutions for a semi linear fractional differential system via Banach fixed point theorem.
Muayyad Mahmood Khalil
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Two-Dimensional Time-Fractional Nonlinear Drift Reaction–Diffusion Equation Arising in Electrical Field

open access: yesFractal and Fractional
Diffusion equations play a crucial role in various scientific and technological domains, including mathematical biology, physics, electrical engineering, and mathematics. This article presents a new formulation of the diffusion equation in the context of
Anjuman, Andrew Y. T. Leung, Subir Das
doaj   +1 more source

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