Results 11 to 20 of about 526,298 (136)

Longitudinal Tumor Size and Survival Modeling for Exposure-Response Analysis of Drugs with Frequent Dose Reductions: Dose Justification of Abemaciclib in Patients with Metastatic Breast Cancer. [PDF]

Clin Pharmacol Ther
Abemaciclib is an oral anticancer drug indicated for treatment of HR+ HER2‐ breast cancer. Dose modifications due to side effects are frequent, thus drug exposures change over time as a result of altering the dose or temporarily withholding abemaciclib treatment.
Chigutsa E, Chapman SC, Turner PK.
europepmc   +2 more sources

Multi-anyons in the magnetic field

, 1998
We consider the external magnetic field effects on the two types of anyon with fractional statistical parameters $p/q$ with coprimes $p$ and $q$, one with fractional charge $e/q $ and flux $p \phi_0(=hc/e)$(type I), the other with fractional flux $p ...
Choi, Taeseung, Kim, Chul Koo, Ryu, Chang-Mo   +2 more
core   +1 more source

${L^p}$-variations for multifractal fractional random walks

, 2008
A multifractal random walk (MRW) is defined by a Brownian motion subordinated by a class of continuous multifractal random measures $M[0,t], 0\le t\le1$.
Ludeña, Carenne
core   +1 more source

Start, Stop, Rewind, Repeat—Cyclic Exposure of Adipose Stromal Cells‐derived Cartilage Organoids to Chondrogenic and Proliferative Cues to Achieve Scaled‐up and Customizable Bone Formation by Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister, Emilien Lhospice, Andrés García‐García, Robert Paillaud, Sebastian Jung, Romain Schaller, Elisabeth A. Kappos, Claude Jaquiéry, Tarek Ismail, Dirk J. Schaefer, Michael de Wild, Ivan Martin, Alexandre Kaempfen, Arnaud Scherberich, Adrien Moya   +14 more
wiley   +1 more source

Linear Fractional p-Adic and Adelic Dynamical Systems

, 2006
Using an adelic approach we simultaneously consider real and p-adic aspects of dynamical systems whose states are mapped by linear fractional transformations isomorphic to some subgroups of GL (2, Q), SL (2, Q) and SL (2, Z) groups.
Albeverio, Andrei Khrennikov, Baake, Brakke, Branko Dragovich, Dolan, Dragovich, Dragovich, Dusan Mihajlovic, Gel'fand, Karwowski, Khamraev, Khrennikov, Khrennikov, Mezard, Mukhamedov, Parisi, Rammal, Roth, Schikhof, Thiran   +20 more
core   +1 more source

Structural Eigenmodes of the Brain to Improve the Source Localization of EEG: Application to Epileptiform Activity

Advanced Science, EarlyView.
Geometry and connectivity are complementary structures, which have demonstrated their ability to represent the brain's functional activity. This study evaluates geometric and connectome eigenmodes as biologically informed constraints for EEG source localization.
Pok Him Siu, Philippa J. Karoly, Sina Mansour L., Artemio Soto‐Breceda, Levin Kuhlmann, Mark J. Cook, David B. Grayden   +6 more
wiley   +1 more source

Quantum and classical solutions for free particle in wedge billiards

, 2000
We have studied the quantum and classical solutions of a particle constrained to move inside a sector circular billiard with angle $\theta_w$ and its pacman complement with angle $2\pi-\theta_w$.
A. Góngora-T, Berry II, Bohigas, Jorge V. José, P.H.E. Tiesinga, Robinett, S. Schaffner, Suhan, Zereadi   +8 more
core   +1 more source

Spectral‐Integrated Thermal Absorption Model for Broadband Laser‐Protective Reflectors Under Supercontinuum Irradiation

Advanced Science, EarlyView.
A universal laser absorption model based on spectral integration enables the design of ultrabroadband dielectric multilayer reflectors for laser protection. The model reveals exponential decay of absorption characterized by two coefficients, and a design that prioritizes short‐wavelength reflection minimizes heating.
Yukang Feng, Yanzhi Wang, Yulin Zhang, Yesheng Lu, Yu Chen, Fanxin Meng, Huisong Hu, Zhongyang Xing, Jianda Shao   +8 more
wiley   +1 more source

Fractional L\'{e}vy-driven Ornstein--Uhlenbeck processes and stochastic differential equations

, 2011
Using Riemann-Stieltjes methods for integrators of bounded $p$-variation we define a pathwise integral driven by a fractional L\'{e}vy process (FLP). To explicitly solve general fractional stochastic differential equations (SDEs) we introduce an Ornstein-
Fink, Holger, Klüppelberg, Claudia
core   +1 more source

Quantitative Stain Mapping in X‐Ray Virtual Histology

Advanced Science, EarlyView.
Virtual histology promises 3D tissue examination without physical sectioning, yet has lacked the tissue‐specificity of conventional pathology. This work demonstrates the first quantitative three‐dimensional stain mapping at histologically relevant resolution, separating contrast agent from tissue to reveal cellular features such as nuclei. The approach
Dominik John, David M. Paganin, Marie‐Christine Zdora, Lisa Marie Petzold, Patrick Ilg, Junan Chen, Sara Baggio, Johannes B. Thalhammer, Sami Wirtensohn, Julian Moosmann, Jörg U. Hammel, Felix Beckmann, Samantha J. Alloo, Jannis N. Ahlers, Madleen Busse, Julia Herzen, Kaye S. Morgan   +16 more
wiley   +1 more source