Altered Fractional Amplitude of Low-Frequency Fluctuation in Anxious Parkinson's Disease. [PDF]
Objective: Anxiety symptoms are persistent in Parkinson’s disease (PD), but the underlying neural substrates are still unclear. In the current study, we aimed to explore the underlying neural mechanisms in PD patients with anxiety symptoms.
Zhang P +7 more
europepmc +7 more sources
Altered Fractional Amplitude of Low-Frequency Fluctuation in Major Depressive Disorder and Bipolar Disorder. [PDF]
Background: Discriminating between major depressive disorder (MDD) and bipolar disorder (BD) remains challenging and cognitive deficits in MDD and BD are generally recognized.
Qiu Y +13 more
europepmc +8 more sources
Abnormalities in the Fractional Amplitude of Low-Frequency Fluctuation and Functional Connectivity in Parkinson's Disease With Excessive Daytime Sleepiness. [PDF]
BackgroundExcessive daytime sleepiness (EDS) is one of the most important non-motor symptoms of Parkinson's disease (PD), and its neuropathologic basis is still unclear.ObjectiveThis study investigated the changes of neuronal activity in PD patients with
Zi Y +14 more
europepmc +7 more sources
Altered Patterns of the Fractional Amplitude of Low-Frequency Fluctuation in Drug-Naive First-Episode Unipolar and Bipolar Depression. [PDF]
Background: An early and correct diagnosis is crucial for treatment of unipolar depression (UD) and bipolar disorder (BD). The fractional amplitude of low-frequency fluctuations (fALFFs) has been widely used in the study of neuropsychiatric diseases, as ...
Chai X +7 more
europepmc +8 more sources
Shared and Distinct Fractional Amplitude of Low-Frequency Fluctuation Patterns in Major Depressive Disorders With and Without Gastrointestinal Symptoms. [PDF]
Objective: Gastrointestinal (GI) symptoms are fairly common somatic symptoms in depressed patients. The purpose of this study was to explore the influence of concomitant GI symptoms on the fractional amplitude of low-frequency fluctuation (fALFF ...
Fu X +6 more
europepmc +8 more sources
Shared and differential fractional amplitude of low-frequency fluctuation patterns at rest in major depressive disorders with or without sleep disturbance. [PDF]
ObjectiveSleep disturbances (SD) are commonly found in patients with major depressive disorder (MDD). This study aims to explore the influence of SD symptoms on clinical characteristics in patients with MDD and to investigate the shared and distinct ...
Zheng N +7 more
europepmc +5 more sources
Altered patterns of fractional amplitude of low-frequency fluctuation and regional homogeneity in abstinent methamphetamine-dependent users. [PDF]
Methamphetamine (MA) could induce functional and structural brain alterations in dependent subjects. However, few studies have investigated resting-state activity in methamphetamine-dependent subjects (MADs).
Xie A +10 more
europepmc +6 more sources
Characteristics of the Fractional Amplitude of Low-Frequency Fluctuation in Ocular Hypertension Patients: A Resting-State fMRI Study. [PDF]
BackgroundThe fractional amplitude of low-frequency fluctuation (fALFF) method has been underutilized in research on the pathogenesis and clinical manifestations of ocular hypertension (OH).PurposeThis study uses resting state functional magnetic ...
Liang Y +9 more
europepmc +5 more sources
Abnormal Fractional Amplitude of Low Frequency Fluctuation Changes in Patients With Dry Eye Disease: A Functional Magnetic Resonance Imaging Study. [PDF]
PurposeTo investigate spontaneous brain activity in patients with dry eye (DE) and healthy control (HC) using the fractional amplitude of low frequency fluctuation (fALFF) technique with the aim of elucidating the relationship between the clinical ...
Liang RB +8 more
europepmc +3 more sources
Abnormal Fractional Amplitude of Low-Frequency Fluctuation as a Potential Imaging Biomarker for First-Episode Major Depressive Disorder: A Resting-State fMRI Study and Support Vector Machine Analysis. [PDF]
Objective: Major depressive disorder (MDD) is a psychiatric disorder with serious negative health outcomes; however, there is no reliable method of diagnosis.
Gao Y +6 more
europepmc +4 more sources

