Results 61 to 70 of about 176,078,744 (269)

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Altered intrinsic brain activity in patients with familial cortical myoclonic tremor and epilepsy: An amplitude of low-frequency fluctuation study

, 2015
Purpose: To investigate localized cerebral function abnormalities in patients with familial cortical myoclonic tremor and epilepsy (FCMTE) using resting-state functional magnetic resonance imaging (fMRI). Methods: Seven patients with FCMTE from a Chinese
Bin, Yi, Yang, Zhenglin, Yao, Dezhong, Wang, Pu, Luo, Cheng, Dong, Li, Ma, Shi, Guo, Fuqiang, Guo, FQ (reprint author), Sichuan Acad Med Sci, Dept Neurol, Chengdu, Sichuan, Peoples R China.   +8 more
core   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Impact of visual repetition rate on intrinsic properties of low frequency fluctuations in the visual network. [PDF]

, 2011
BACKGROUND: Visual processing network is one of the functional networks which have been reliably identified to consistently exist in human resting brains. In our work, we focused on this network and investigated the intrinsic properties of low frequency (
Chien-Chung Chen, Li, Yi-Chia; Chen, Chien-Chung; Chen, Jyh-Horng; Valdes-Sosa, Pedro Antonio, Li Yi-Chia, Chen Chien-Chung, Jyh-Horng Chen, Chen Jyh-Horng, Yi-Chia Li   +6 more
core   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source

Searchlight classification based on Amplitude of Low Frequency Fluctuation and functional connectivity in individuals with obsessive-compulsive symptoms

, 2019
Introduction: Investigating obsessive-compulsive symptoms in subclinical populations provides a useful framework for understanding the early development of obsessive-compulsive spectrum disorders.
Sørensen, TA, Chan, RCK, Chan, Raymond C.K., Cheung, Eric F.C., Zhang, Rui Ting, Wang, Yong-ming, Cai, Xin Lu, Cai, Xin-lu, Wang, YM, Møller, Arne, Madsen, KH, Chan, Raymond C. K., Wang, Y, Cheung, EFC, Sorensen, Thomas Alrik, Zhang, Rui-ting, Moller, Arne, Wang, Yong Ming, Wang, Yi, Cai, XL, Sørensen, Thomas Alrik, Sørensen, Thomas Alrik; id_orcid, Madsen, Kristoffer Hougaard, Cheung, Eric F. C., Zhang, RT, Møller, A   +25 more
core   +1 more source

Transdiagnostic markers across the psychosis continuum: a systematic review and meta-analysis of resting state fMRI studies

Frontiers in Psychiatry
Psychotic symptoms are among the most debilitating and challenging presentations of severe psychiatric diseases, such as schizophrenia, schizoaffective, and bipolar disorder.
Giuseppe Pierpaolo Merola, Livio Tarchi, Luigi F. Saccaro, Farnaz Delavari, Farnaz Delavari, Camille Piguet, Camille Piguet, Dimitri Van De Ville, Dimitri Van De Ville, Giovanni Castellini, Valdo Ricca   +10 more
doaj   +1 more source

Altered spontaneous brain activity patterns in hypertensive retinopathy using fractional amplitude of low-frequency fluctuations: a functional magnetic resonance imaging study [PDF]

International Journal of Ophthalmology
AIM: To study functional brain abnormalities in patients with hypertensive retinopathy (HR) and to discuss the pathophysiological mechanisms of HR by fractional amplitude of low-frequency fluctuations (fALFFs) method.
Xue-Lin Wang, Xu-Jun Zheng, Li-Juan Zhang, Jin-Yu Hu, Hong Wei, Qian Ling, Liang-Qi He, Cheng Chen, Yi-Xin Wang, Xu Chen, Yi Shao   +10 more
doaj   +1 more source

Delay discounting is associated with the fractional amplitude of low-frequency fluctuations and resting-state functional connectivity in late adolescence [PDF]

Scientific Reports, 2017
AbstractAs a component of self-regulation, delay discounting (DD) refers to an individual’s tendency to prefer smaller-but-sooner rewards over larger-but-later rewards and plays an essential role in many aspects of human behavior. Although numerous studies have examined the neural underpinnings of DD in adults, there are far fewer studies focusing on ...
Wang, Song, Zhou, Ming, Chen, Taolin, Yang, Xun, Chen, Guangxiang, Gong, Qiyong   +5 more
openaire   +2 more sources

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source