Results 91 to 100 of about 187,262 (303)

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

Orthonormal piecewise Vieta-Lucas functions for the numerical solution of the one- and two-dimensional piecewise fractional Galilei invariant advection-diffusion equations

open access: yesJournal of Advanced Research, 2023
Introduction: Recently, a new family of fractional derivatives called the piecewise fractional derivatives has been introduced, arguing that for some problems, each of the classical fractional derivatives may not be able to provide an accurate statement ...
Mohammad Hossein Heydari   +2 more
doaj  

Fractional Derivatives, Splines And Tomography

open access: yes, 2000
Publication in the conference proceedings of EUSIPCO, Tampere, Finland ...
Unser, Michael   +2 more
openaire   +3 more sources

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

Fractional Brownian Motion as a Differentiable Generalized Gaussian Process [PDF]

open access: yes
Brownian motion can be characterized as a generalized random process and, as such, has a generalized derivative whose covariance functional is the delta function. In a similar fashion, fractional Brownian motion can be interpreted as a generalized random
Peter C.B. Phillips   +1 more
core  

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Comparative study of integer-order and fractional-order artificial neural networks: Application for mathematical function generation

open access: yese-Prime: Advances in Electrical Engineering, Electronics and Energy
This paper investigates the impact of fractional derivatives on the activation functions of an artificial neural network (ANN). Based on the results and analysis, a three-layer backpropagation neural network model with fractional and integer derivatives ...
Manisha Premkumar Joshi   +2 more
doaj  

Fractional thermal diffusion and the heat equation

open access: yesOpen Physics, 2015
Fractional calculus is the branch of mathematical analysis that deals with operators interpreted as derivatives and integrals of non-integer order. This mathematical representation is used in the description of non-local behaviors and anomalous complex ...
Gómez Francisco   +4 more
doaj   +1 more source

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