Results 131 to 140 of about 595,099 (300)

A new definition of fractional derivative

Journal of Computational and Applied Mathematics, 2014
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Roshdi Khalil, Mohammed Al Horani, Abdelrahman Yousef, Mohammad Sababheh   +3 more
openaire   +2 more sources

On Extended Caputo Fractional Derivative Operator

, 2017
The main objective of this present paper is to introduce further extension of extended Caputo fractional derivative operator and establish the extension of an extended fractional derivative of some known elementary functions.
Gauhar Rahman, Muhammad Arshad, Kottakkaran Sooppy Nisar   +2 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Time fractional IHCP with Caputo fractional derivatives

Computers & Mathematics with Applications, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Proposal for use of the fractional derivative of radial functions in interpolation problems

This paper presents the construction of a family of radial functions aimed at emulating the behavior of the radial basis function known as thin plate spline (TPS). Additionally, a method is proposed for applying fractional derivatives, both partially and
Brambila Paz, Fernando, Ramírez, Rafael, 1966-, Torres Hernandez, Anthony   +2 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

New Approach for the Analysis of Damped Vibrations of Fractional Oscillators

Shock and Vibration, 2009
The dynamic behavior of linear and nonlinear mechanical oscillators with constitutive equations involving fractional derivatives defined as a fractional power of the operator of conventional time-derivative is considered.
Yuriy A. Rossikhin, Marina V. Shitikova
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Fractional Systems with Multi-Parameters Fractional Derivatives

International Journal of Theoretical Physics
Abstract Recently, a generalization of fractional variational formulations in terms of multiparameter fractional derivatives was introduced by Agrawal and Muslih. This treatment can be used to obtain the Lagrangian and Hamiltonian equations of motion.
Muslih, Sami I., Agrawal, Om P., Baleanu, Dumitru   +2 more
openaire   +1 more source