Results 201 to 210 of about 2,052,042 (321)

Study on nonlinear creep damage model based on fractional derivative. [PDF]

Sci Rep
Li G, Jia H.
europepmc   +1 more source

Dynamics of chaotic system based on circuit design with Ulam stability through fractal-fractional derivative with power law kernel. [PDF]

Sci Rep, 2023
Khan N, Ahmad Z, Shah J, Murtaza S, Albalwi MD, Ahmad H, Baili J, Yao SW.   +7 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Mathematical modeling of tuberculosis using Caputo fractional derivative: a comparative analysis with real data. [PDF]

Sci Rep
Bhatter S, Kumawat S, Purohit SD, Suthar DL.   +3 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Explicit solutions of the generalized Kudryashov's equation with truncated M-fractional derivative. [PDF]

Sci Rep
Gu M, Liu F, Li J, Peng C, Li Z.
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

On generalized fractal-fractional derivative and integral operators associated with generalized Mittag-Leffler function. [PDF]

Heliyon
Khan H, Rahman G, Samraiz M, Shah K, Abdeljawad T.   +4 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Correction: Solution of time-fractional gas dynamics equation using Elzaki decomposition method with Caputo-Fabrizio fractional derivative. [PDF]

PLoS One
Sadaf M, Perveen Z, Akram G, Habiba U, Abbas M, Emadifar H.   +5 more
europepmc   +1 more source