Results 151 to 160 of about 1,816,969 (371)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Heat transfer of generalized second grade fluid with MHD, radiation and exponential heating using Caputo-Fabrizio fractional derivatives approach. [PDF]
Sci Rep, 2023 Sehra S +5 more
europepmc +1 more source
Uniqueness in determining the orders of time and spatial fractional derivatives [PDF]
, 2020 Masahiro Yamamoto
openalex +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
International Journal of Mathematics for IndustryThis paper aims to contribute to and broaden the current understanding of fractional calculus and its uses in science. In general, determining the fractional derivative of a product of two functions is an obstacle.
Rami AlAhmad +2 more
doaj +1 more source
A Complete Model of Crimean-Congo Hemorrhagic Fever (CCHF) Transmission Cycle with Nonlocal Fractional Derivative [PDF]
, 2021 Hakimeh Mohammadi +4 more
openalex +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Role of fractional derivatives in the mathematical modeling of the transmission of Chlamydia in the United States from 1989 to 2019. [PDF]
Nonlinear Dyn, 2023 Vellappandi M, Kumar P, Govindaraj V.
europepmc +1 more source