Results 81 to 90 of about 40,668 (308)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
e-Prime: Advances in Electrical Engineering, Electronics and EnergyThis paper investigates the impact of fractional derivatives on the activation functions of an artificial neural network (ANN). Based on the results and analysis, a three-layer backpropagation neural network model with fractional and integer derivatives ...
Manisha Premkumar Joshi +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
On Riemann-Liouville and Caputo Derivatives
Discrete Dynamics in Nature and Society, 2011 Recently, many models are formulated in terms of fractional derivatives, such as in control processing, viscoelasticity, signal processing, and anomalous diffusion. In the present paper, we further study the important properties of the Riemann-Liouville (
Changpin Li, Deliang Qian, YangQuan Chen
doaj +1 more source
MR-Metric Spaces: Theory and Applications in Fractional Calculus and Fixed-Point Theorems [PDF]
Neutrosophic Sets and SystemsThis paper investigates the interplay between MR-metric spaces and fractional calculus, estab lishing new theoretical results with applications in analysis and mathematical physics.
Abed Al-Rahman M. Malkawi +1 more
doaj +3 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Economic Interpretation of Fractional Derivatives [PDF]
Progress in Fractional Differentiation and Applications, 2017 10 pages, 2 figures ...
Tarasova, Valentina V. +1 more
openaire +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Abstract and Applied Analysis, 2014 We study fractional-order derivatives of left-handed Grünwald-Letnikov formula with ...
Shaoxiang Hu, Ping Liang
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source