Results 111 to 120 of about 191,994 (333)

Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism

open access: yesFEBS Open Bio, EarlyView.
In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki   +3 more
wiley   +1 more source

Analogue of Newton-Puiseux series for non-holonomic D-modules and factoring

open access: yes, 2008
We introduce a concept of a fractional-derivatives series and prove that any linear partial differential equation in two independent variables has a fractional-derivatives series solution with coefficients from a differentially closed field of zero ...
Grigoriev, D.
core   +1 more source

Structural and functional characterization of chitinase from carnivorous plant Drosera adelae

open access: yesFEBS Open Bio, EarlyView.
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda   +7 more
wiley   +1 more source

ON ASYMPTOTICS OF SOME FRACTIONAL DIFFERENTIAL EQUATIONS

open access: yesMathematical Modelling and Analysis, 2013
In this paper we study the large-argument asymptotic behaviour of certain fractional differential equations with Caputo derivatives. We obtain exponential and algebraic asymptotic solutions. The latter, decaying asymptotics differ significantly from the integer-order derivative equations.
openaire   +5 more sources

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

open access: yesFEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó   +7 more
wiley   +1 more source

Application of piecewise fractional differential equation to COVID-19 infection dynamics. [PDF]

open access: yesResults Phys, 2022
Li XP   +6 more
europepmc   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

open access: yesFEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová   +11 more
wiley   +1 more source

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