Results 111 to 120 of about 537,797 (362)

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Lyapunov-type inequality for a fractional differential equation with fractional boundary conditions

, 2015
In this paper, a Lyapunov-type inequality is obtained for a fractional differential equation under fractional boundary conditions. We then use this inequality to obtain an interval where a certain Mittag-Leffler function has no real zeros.
Jianxun Rong, C. Bai
semanticscholar   +1 more source

Stability Of Fractional Differential Equation

, 2013
{"references": ["", "R.P. Agarwal, D. O'Regan, Singular boundary value problems for superlinear\nsecond order ordinary and delay differential equations, J.\nDifferential Equations 130 (1996) 333-335.", "R.P. Agarwal, D. O'Regan, V. Lakshmikantham, Quadratic forms and\nnonlinear non-resonant singular second order boundary value problems\nof limit circle
openaire   +1 more source

ON ASYMPTOTICS OF SOME FRACTIONAL DIFFERENTIAL EQUATIONS

Mathematical Modelling and Analysis, 2013
In this paper we study the large-argument asymptotic behaviour of certain fractional differential equations with Caputo derivatives. We obtain exponential and algebraic asymptotic solutions. The latter, decaying asymptotics differ significantly from the integer-order derivative equations.
openaire   +5 more sources

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Comparison of third-order fractional partial differential equation based on the fractional operators using the explicit finite difference method

Alexandria Engineering Journal, 2023
In this research paper, the third-order fractional partial differential equation (FPDE) in the sense of the Caputo fractional derivative and the Atangana-Baleanu Caputo (ABC) fractional derivative is investigated for the first time. The importance of the
Shorish Omer Abdulla, Sadeq Taha Abdulazeez, Mahmut Modanli   +2 more
doaj  

Fractional Differential Equations 2011 [PDF]

International Journal of Differential Equations, 2011
Liu, Fawang, Agrawal, Om P., Momani, Shaher, Leonenko, Nikolai N., Chen, Wen   +4 more
openaire   +4 more sources

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

FEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada, Kouhei Ohtani, Pushpa Kiran Gullapalli, Kazuhiko Ishikawa   +3 more
wiley   +1 more source

Existence and uniqueness of the solution to uncertain fractional differential equation

, 2015
The paper proves an existence and uniqueness theorem of the solution to an uncertain fractional differential equation by Banach fixed point theorem under Lipschitz and linear growth conditions.
Yuanguo Zhu
semanticscholar   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source