Results 161 to 170 of about 29,097 (308)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Stability analysis for a class of implicit fractional differential equations involving Atangana-Baleanu fractional derivative. [PDF]

Adv Differ Equ, 2021
Asma, Shabbir S, Shah K, Abdeljawad T.
europepmc   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Non-linear System of Multi-order Fractional Differential Equations: Theoretical Analysis and a Robust Fractional Galerkin Implementation. [PDF]

J Sci Comput, 2022
Faghih A, Mokhtary P.
europepmc   +1 more source

On Fractional Differential Equations

, 2015
In this thesis, we collect some results on sufficient conditions for the existence and unique of solutions for various classes of initial and boundary value problem for fractional differential equations involving the Caputo fractional derivative. Although the tools of fractional calculus have been available and applicable to various fields of study ...
openaire   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie, Xiaotong Li, Venkata Sita Priyanka Illapani, Leigh N. Sepeta, Jason Schroeder, Chima O. Oluigbo, Madison M. Berl, William D. Gaillard, Nathan T. Cohen   +8 more
wiley   +1 more source

Existence and data dependence results for fractional differential equations involving atangana-baleanu derivative. [PDF]

Rend Circ Mat Palermo, 2022
Sutar ST, Kucche KD.
europepmc   +1 more source

Application of Modified Laplace Variational Iteration Hybrid Approach for Solving Time-Fractional Fourth-Order Parabolic PDEs

Journal of Applied Mathematics
The current study is aimed at obtaining analytical solutions of fourth-order parabolic partial differential equations of time-fractional derivative with variable coefficients.
Mehari Fentahun Endalew, Xiaoming Zhang
doaj   +1 more source

Multiple and Nonexistence of Positive Solutions for a Class of Fractional Differential Equations with p-Laplacian Operator

Research about multiple positive solutions for fractional differential equations is very important. Based on some outstanding results reported in this field, this paper continue the focus on this topic.
Bohner, Martin, Zhang, Haoran, Zhaocai Hao, Hao, Zhaocai, Haoran Zhang, Martin Bohner   +5 more
core   +1 more source

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis From ELSA‐Brasil

Arthritis Care &Research, EarlyView.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada, Marcos Rafael N. Cavalcante, Itamar de Souza Santos, Márcio S. Bittencourt, Vandrize Meneghini, Paulo A. Lotufo, Alessandra C. Goulart, Isabela M. Bensenor   +7 more
wiley   +1 more source