A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng +13 more
wiley +1 more source
Association between serum uric acid and urinary uric acid excretion indicators and early impaired kidney function in newly diagnosed T2DM patients with normal serum uric acid levels: a retrospective study. [PDF]
Li X, Zhang X.
europepmc +1 more source
Transposase‐Assisted Donor Tethering Boosts Large‐Fragment HDR in Plants
A transposase‐assisted donor tethering strategy is developed to enhance homology‐directed repair in plants. By recruiting donor DNA to double‐strand breaks and synergizing with repair pathway reprogramming and transcription‐coupled donor design, this system markedly improves large‐fragment targeted insertion efficiency, providing a robust platform for ...
Sha Wei +8 more
wiley +1 more source
Hyponatremia: Evolving diagnostics and emerging therapeutics in clinical practice. [PDF]
Martínez-Sánchez FD +10 more
europepmc +1 more source
Assessing the utility of fractional excretion of urea in distinguishing intrinsic and prerenal acute kidney injury in hospitalised patients: a systematic review and meta-analysis. [PDF]
Pan HC +7 more
europepmc +1 more source
Reevaluation of urinary calcium excretion as a criterion for surgery in primary hyperparathyroidism: a study on nephrolithiasis risk. [PDF]
Omi Y +6 more
europepmc +1 more source
Hepatic dysfunction, hyperuricemia, and multiple renal cysts in adolescence: A case report with HNF1B deficiency and literature review. [PDF]
Yang Y +9 more
europepmc +1 more source
Immune Checkpoint Inhibitor-Induced Endocrine Dysfunction: Early Detection of Symptoms and Timely Intervention. [PDF]
Obaed NG +5 more
europepmc +1 more source
Electrolyte homeostasis in pregnancy: from physiological adaptations to clinical disturbances - a nephrologist's perspective. [PDF]
Meena P, Batool A.
europepmc +1 more source

