Results 141 to 150 of about 17,442 (284)

The cardiac wound healing response to myocardial infarction

open access: yesWIREs Mechanisms of Disease, Volume 15, Issue 1, January/February 2023., 2023
Cardiac wound healing after myocardial infarction is a balance between the breakdown of existing and the construction of new extracellular matrix, with inflammation feeding into both sides. Abstract Myocardial infarction (MI) is defined as evidence of myocardial necrosis consistent with prolonged ischemia.
Upendra Chalise   +2 more
wiley   +1 more source

Evaluating the impact of fractional flow reserve-guided percutaneous coronary intervention in intermediate coronary artery lesions on the mode of treatment and their outcomes: An Iranian experience

open access: yesARYA Atherosclerosis, 2015
BACKGROUND: Today, the fractional flow reserve (FFR) guides the physician to select suitable patients with intermediate severity coronary lesions in angiography that should be treated or not with stent. The aim of this study was to evaluate the impact of
Alireza Khosravi   +7 more
doaj  

Comparative Analysis of the Feasibility of Myocardial Blood Flow Index Versus CT-FFR in the Diagnosis of Suspected Coronary Artery Disease

open access: yesReviews in Cardiovascular Medicine
Background: Using fluid dynamic modeling, noninvasive fractional flow reserve (FFR) derived from coronary computed tomography angiography (CCTA) data provides better anatomic and functional information than CCTA, with a high diagnostic and discriminatory
Qing-feng Xiong   +5 more
doaj   +1 more source

Inter‐atrial block as a predictor of adverse outcomes in patients with HFpEF

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Inter‐atrial block (IAB), a marker of electrical atrial dysfunction, is associated with an increased risk of atrial fibrillation (AF) and adverse events in various populations. The prognostic impact of IAB in heart failure (HF) with preserved ejection fraction (HFpEF) remains unknown.
Jerremy Weerts   +11 more
wiley   +1 more source

The effect of trimetazidine on cardiac haemodynamics and mitochondrial function in wild‐type transthyretin amyloidosis

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Wild‐type transthyretin cardiac amyloidosis (ATTRwt) is a cardiomyopathy causing myocardial hypoperfusion and impaired cardiac mitochondrial function. Trimetazidine is an antianginal agent used in patients with stable angina pectoris, which improves cardiac contractility and mitochondrial function.
Bertil Thyrsted Ladefoged   +5 more
wiley   +1 more source

Effect of sodium‐glucose cotransporter 2 inhibitors on the rate of decline in kidney function: A systematic review and meta‐analysis 钠‐葡萄糖共转运蛋白2抑制剂对肾功能下降速度的影响:系统综述和meta分析

open access: yesJournal of Diabetes, Volume 15, Issue 1, Page 58-70, January 2023., 2023
Highlights Sodium/glucose cotransporter‐2 inhibitors (SGLT‐2i) showed an important renoprotective effect on sustained administration, regardless of the presence of diabetes, the baseline estimated glomerular filtration rate (eGFR) and different types of SGLT‐2i. There was an acute decline of eGFR in the initial administration (4.02 ml/min/1.73 m2), and
Yanbei Duo   +3 more
wiley   +1 more source

State of precision medicine for heart failure with preserved ejection fraction in a new therapeutic age

open access: yesESC Heart Failure, EarlyView.
Abstract Heart failure with preserved ejection fraction (HFpEF) is defined by heart failure (HF) with a left ventricular ejection fraction (LVEF) of at least 50%. HFpEF has a complex and heterogeneous pathophysiology with multiple co‐morbidities contributing to its presentation. Establishing the diagnosis of HFpEF can be challenging.
Roy Rasalam   +4 more
wiley   +1 more source

The efficacy of PDE5 inhibitors in diabetic patients

open access: yesAndrology, Volume 11, Issue 2, Page 245-256, February 2023., 2023
Abstract Background Phosphodiesterase 5 inhibitors (PDE5i), since their introduction in the late 1990s, have proven their efficacy in treating several conditions, predominantly pulmonary hypertension and erectile dysfunction where they remain the first‐line therapeutic option.
Agnieszka Swiecicka
wiley   +1 more source

Clinical usefulness of instantaneous wave-free ratio for the evaluation of coronary artery lesion with prior myocardial infarction: A multi-center study

open access: yesInternational Journal of Cardiology: Heart & Vasculature, 2020
Background: Fractional flow reserve (FFR) is useful for assessing the functional significance of coronary artery stenosis, even in lesions with prior myocardial infarction (pMI).
Shusuke Fukuoka   +10 more
doaj  

Whole-heart dynamic three-dimensional magnetic resonance perfusion imaging for the detection of coronary artery disease defined by fractional flow reserve: determination of volumetric myocardial ischaemic burden and coronary lesion location [PDF]

open access: yes, 2017
Aims Dynamic three-dimensional-cardiac magnetic resonance (3D-CMR) perfusion proved highly diagnostic for the detection of angiographically defined coronary artery disease (CAD) and has been used to assess the efficacy of coronary stenting procedures ...
Boesiger, Peter   +16 more
core  

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