FFR post-PCI: what we learned from the FFR-SEARCH study
WHAT DO WE KNOW ABOUT FRACTIONAL FLOW RESERVE AFTER STENTING? The introduction of the concept of fractional flow reserve (FFR) in the mid 90s moved coronary physiology from experimental science to routine use at the cath lab.1-3 Added to the better ...
Nico H.J. Pijls, Lokien X. van Nunen
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Fractional flow reserve-guided management in stable coronary disease and acute myocardial infarction: recent developments [PDF]
Coronary artery disease (CAD) is a leading global cause of morbidity and mortality, and improvements in the diagnosis and treatment of CAD can reduce the health and economic burden of this condition.
Berry, Colin +5 more
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Background Concerns exist about reliability of pressure‐wire‐guided coronary revascularization of non‐infarct‐related arteries (non‐IRA). We investigated whether physiological assessment of non‐IRA during the subacute phase of myocardial infarction might
Hernán Mejía‐Rentería +15 more
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Meta-analysis of death and myocardial infarction in the DEFINE-FLAIR and iFR-SWEDEHEART trials: a hypothesis generating note of caution [PDF]
In patients with coronary heart disease, revascularization can improve symptoms and in certain high-risk subgroups may improve prognosis. Coronary angiography provides anatomical information and the physiological significance of a stenosis can be ...
Berry, Colin +2 more
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Myocardial Contrast Stress Echo Versus Fractional Flow Reserve [PDF]
The ischemic potential of a coronary artery stenosis is revealed by physiological challenges, manifesting as myocardial malperfusion, and depending on the severity and duration of ischemia, mechanical and electric dysfunctions. Coronary pathophysiological changes can be measured either directly by translesional coronary pressure and flow or indirectly ...
Morton J, Kern, Arnold H, Seto
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Fractional Flow Reserve–Negative High-Risk Plaques and Clinical Outcomes After Myocardial Infarction [PDF]
ImportanceEven after fractional flow reserve (FFR)–guided complete revascularization, patients with myocardial infarction (MI) have high rates of recurrent major adverse cardiovascular events (MACE). These recurrences may be caused by FFR-negative high-risk nonculprit lesions.ObjectiveTo assess the association between optical coherence tomography (OCT)-
Mol, J.H.Q. +23 more
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Influence of contrast media dose and osmolality on the diagnostic performance of contrast fractional flow reserve [PDF]
Background—Contrast fractional flow reserve (cFFR) is a method for assessing functional significance of coronary stenoses, which is more accurate than resting indices and does not require adenosine.
Berry, Colin +10 more
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Myocardial perfusion MRI compared to fractional flow reserve: a meta-analysis [PDF]
Methods This meta-analysis was performed in adherence to the PRISMA statement. Two reviewers systematically searched PubMed, EMBASE and Web of Science, using predefined inclusion and exclusion criteria. Only studies using invasive coronary angiography combined with FFR for assessment of intermediate coronary stenoses were included.
Takx, Richard +3 more
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Background: Coronary angiography alone is insufficient to identify lesions associated with myocardial ischemia that may benefit from revascularization.
Valerie Stegehuis +13 more
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Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need [PDF]
The diagnostic management of patients with angina pectoris typically centres on the detection of obstructive epicardial CAD, which aligns with evidence-based treatment options that include medical therapy and myocardial revascularisation.
Berry, Colin +2 more
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