Results 151 to 160 of about 301,214 (427)
Abstract Objective We measured clinical and quantitative MRI outcome measures in CMT1A to assess long‐term responsiveness, establish longitudinal validity and assess MRI as a bridging biomarker. Methods Twenty patients with CMT1A and 20 matched controls underwent MRI, myometry and clinical assessments up to four times over mean 4‐year follow‐up ...
Matthew R. B. Evans+8 more
wiley +1 more source
Clinical Outcomes of physiologically-guided revascularisation [PDF]
Objective: To assess the clinical outcomes of revascularisation based on fractional flow reserve (FFR) and/or instantaneous wave-free ratio (iFR).Study design: Descriptive study.Place and duration of study: Department of Medicine, The Aga Khan University
Adnan, Ghufran+4 more
core +1 more source
Targeted Long‐Read Sequencing as a Single Assay Improves the Diagnosis of Spastic‐Ataxia Disorders
ABSTRACT Objective The hereditary spastic‐ataxia spectrum disorders are a group of disabling neurological diseases. The traditional genetic testing pathway is complex, multistep and leaves many cases unsolved. We aim to streamline and improve this process using long‐read sequencing. Methods We developed a targeted long‐read sequencing strategy with the
Laura Ivete Rudaks+20 more
wiley +1 more source
Assessment of myocardial ischemia in patients with stable angina is important in deciding whether to treat coronary artery disease and in predicting clinical outcome.
Sung Min Ko
doaj +1 more source
Physics driven reduced order model for real time blood flow simulations [PDF]
Predictive modeling of blood flow and pressure have numerous applications ranging from non-invasive assessment of functional significance of disease to planning invasive procedures. While several such predictive modeling techniques have been proposed, their use in the clinic has been limited due in part to the significant time required to perform ...
arxiv
Fractional Flow Reserve in Acute Coronary Syndromes ∗
The clinical utility of measuring fractional flow reserve (FFR) in the cardiac catheterization laboratory to guide the decision regarding coronary revascularization is now well established.
Nico H.J. Pijls+3 more
openaire +3 more sources
Considering the Risks and Costs of Solid Organ Xenotransplantation
This perspective discusses the rationale, risks, and costs of whole‐organ xenotransplantation. It considers alternative strategies to obviate the demand for transplants and optimize allotransplantation systems and practices that do not impose xenotransplantation's harms and risks, and whether they are the most ethical and effective means to increase ...
Catharine E. Krebs+5 more
wiley +1 more source
Background Fractional flow reverse (FFR) is the gold standard assessment of the hemodynamic significance of coronary stenoses. However, it requires the catheterization of the coronary artery to determine the pressure waveforms proximal and distal to the ...
R. Agujetas+3 more
doaj +1 more source
Fractional flow reserve by computerized tomography and subsequent coronary revascularization [PDF]
AIMS: Fractional flow reserve by computerized tomography (FFR-CT) provides non-invasive functional assessment of the hemodynamic significance of coronary artery stenosis. We determined the FFR-CT values, receiver operator characteristic (ROC) curves, and
Budoff, Matthew J+3 more
core +2 more sources