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Structuring BaTiO3 /PDMS Nanocomposite via Dielectrophoresis for Fractional Flow Reserve Measurement
Advanced Engineering Materials, 2021This work focuses on the development of piezoelectric sensors for the fractional flow reserve (FFR) technique, a procedure based on the measurement of blood pressure within a vessel to evaluate the severity of coronary stenosis.
Giulia D'ambrogio +7 more
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Understanding Fractional Flow Reserve
2017Invasive functional evaluation of epicardial coronary stenoses is increasingly utilized in order to target treatment of obstructive coronary artery disease (CAD) to ischemia-producing lesions. Fractional flow reserve (FFR) has been validated against noninvasive stress testing showing high accuracy for the detection of ischemia-producing coronary ...
Leone AM, Scalone G, Niccoli G
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Landmark Fractional Flow Reserve Trials
Interventional Cardiology Clinics, 2015Fractional flow reserve (FFR) has become widely used for physiologic assessment of intermediate coronary lesions. The Fractional Flow Reserve to Determine Appropriateness of Angioplasty in Moderate Coronary Stenoses (DEFER) trial established the safety of deferring angioplasty for moderate lesions that are not functionally significant.
William F. Fearon, Donald R. Lynch
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2021
Fractional flow reserve is an index of the physiological significance of a coronary stenosis, defined as the ratio of maximal myocardial blood flow in the presence of the stenosis to the theoretically normal maximal myocardial blood flow (i.e. in the absence of the stenosis).
Giovanni Ciccarelli +2 more
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Fractional flow reserve is an index of the physiological significance of a coronary stenosis, defined as the ratio of maximal myocardial blood flow in the presence of the stenosis to the theoretically normal maximal myocardial blood flow (i.e. in the absence of the stenosis).
Giovanni Ciccarelli +2 more
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Fractional flow reserve: a review
Heart, 2008Coronary angiography remains far and away the most accurate morphologic assessment of the lumen of the epicardial coronary arteries. Although non-invasive imaging is rapidly advancing, the temporal and spatial resolution of coronary angiography is still unsurpassed and it will therefore remain as a roadmap for interventional cardiologists and cardiac ...
B. De Bruyne, Jaydeep Sarma
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Influence of zero flow pressure on fractional flow reserve
Biomechanics and Modeling in Mechanobiology, 2004Fractional flow reserve (FFR) is a commonly used index to assess the functional severity of a coronary artery stenosis. It is conventionally calculated as the ratio of the pressure distal (Pd) and proximal (Pa) to the stenosis (FFR= Pd/Pa). We hypothesize that the presence of a zero flow pressure (Pzf), requires a modification of this equation. Using a
Claessens, T.E. +5 more
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Image-based assessment of fractional flow reserve
EuroIntervention, 2015Pressure-derived fractional flow reserve (FFR) is an index of the haemodynamic significance of a coronary lesion. Numerous studies have provided robust evidence that FFR-guided percutaneous coronary intervention is associated with better clinical outcomes and reduces the need for repeat revascularisation.
Tu, Shengxian +5 more
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The fallacies of fractional flow reserve
International Journal of Cardiology, 2020David L. Brown, Andrea Soares
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Validation of Fractional Flow Reserve in Animals
1997During maximum vasodilation, which corresponds with minimal myocardial resistance, distal coronary pressure divided by aortic pressure equals maximum myocardial blood flow divided by the normally expected value as it would be if no epicardial lesion were present1,2.
Bernard De Bruyne, Nico H. J. Pijls
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