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Comparison of standard- and high-dose intracoronary adenosine for the measurement of coronary fractional flow reserve (FFR)

Clinical Research in Cardiology, 2016
Measurement of fractional flow reserve (FFR) by intravenous infusion or intracoronary injection of adenosine is the reference method to determine the hemodynamic relevance of coronary artery stenoses. The goal of this prospective study was to compare standard (40 µg adenosine for the right and 80 µg for the left coronary artery) to high doses of ...
Mohamed Marwan   +2 more
exaly   +3 more sources

Fractional flow reserve (FFR) as a guide to treat coronary artery disease

Expert Review of Cardiovascular Therapy, 2018
The presence and extent of myocardial ischemia are the major determinants of prognosis in patients with coronary artery disease (CAD). Unlike coronary angiography alone, fractional flow reserve (FFR) has enabled interventional cardiologists to accurately determine whether coronary atherosclerotic plaques are responsible for myocardial ischemia, and ...
Mangiacapra, Fabio   +4 more
openaire   +5 more sources

Determination of fractional flow reserve (FFR) based on scaling laws: a simulation study

Physics in Medicine and Biology, 2008
Fractional flow reserve (FFR) provides an objective physiological evaluation of stenosis severity. A technique that can measure FFR using only angiographic images would be a valuable tool in the cardiac catheterization laboratory. To perform this, the diseased blood flow can be measured with a first pass distribution analysis and the theoretical normal
Jerry T, Wong, Sabee, Molloi
openaire   +2 more sources

Intracoronary Hemodynamic Assessment: Coronary Flow Reserve (CFR) and Fractional Flow Reserve (FFR)

2012
Selective coronary angiography is the gold standard for evaluating the presence and extent of epicardial coronary artery disease. Despite advances in fluoroscopic imaging and catheterization techniques, the evaluation of the intermediate coronary stenosis (luminal diameter narrowing between 40 and 70 %) remains a challenge for invasive cardiologists ...
James E. Harvey, Stephen G. Ellis
openaire   +1 more source

Abstract 472: Fractional Flow Reserve (FFR): FAR FROM REALITY

Arteriosclerosis, Thrombosis, and Vascular Biology, 2013
Fractional Flow Reserve (FFR) is the ratio of maximal blood flow in a stenotic artery to normal maximal flow. It is the “gold standard” technique used in diagnostic angiography to determine whether percutaneous intervention is needed in a moderate coronary stenosis (estimated 50-70% lesion).
Chintan Patel   +2 more
openaire   +1 more source

Fractional flow reserve (FFR): changing the practice of interventional cardiology.

Minerva cardioangiologica, 2012
Fractional flow reserve (FFR) has become an extremely valuable tool for assessing the hemodynamic significance of intermediate coronary lesions. This manuscript delineates the current guidelines regarding the use of FFR and discusses emerging indications for the use of this diagnostic tool and how they compare with and complement non-invasive or other ...
E, Kaluski   +8 more
openaire   +1 more source

The Guiding Significance of Fractional Flow Reserve (FFR) for Coronary Heart Disease Revascularization.

Discovery medicine, 2022
Coronary angiography is an important diagnostic tool for coronary heart disease. While it can identify anatomical coronary stenosis, its ability to identify hemodynamic changes is limited. The Fractional Flow Reserve (FFR) technique, combined with coronary angiography, facilitates both the functional and anatomical assessment of heart disease.
Maodong, Yang   +4 more
openaire   +1 more source

Single centre experience using vessel Fractional Flow Reserve (vFFR) and diagnostic performance compared with invasive Fractional Flow Reserve (FFR)

European Heart Journal
Abstract Background Fractional flow reserve (FFR) is a diagnostic gold standard in the functional assessment of coronary artery stenoses (1). Alternative invasive and non-invasive methods have been developed in an attempt to avoid limitations associated with FFR including added procedural risk ...
B Traynor   +10 more
openaire   +1 more source

Artificial Intelligence Analysis of ECG to Determine Fractional Flow Reserve (FFR)

Abstract Background The current gold standard of coronary artery disease (CAD) diagnosis is invasive angiography, during which fractional flow reserve (FFR) measurement may be performed to confirm the clinical significance of a stenosis.
Łukasz Kalińczuk   +10 more
openaire   +1 more source

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