Results 141 to 150 of about 104,407 (324)

The Extended Bessel-Maitland Function and Integral Operators Associated with Fractional Calculus

Journal of Mathematics, 2020
The aim of this paper is to introduce a presumably and remarkably altered integral operator involving the extended generalized Bessel-Maitland function. Particular properties are considered for the extended generalized Bessel-Maitland function connected ...
Kelelaw Tilahun, Hagos Tadessee, D. L. Suthar   +2 more
doaj   +1 more source

Variable Herz Estimates for Fractional Integral Operators

Ukrainian Mathematical Journal, 2020
UDC 517.5 In this paper, the author study the boundedness of fractional integral operators on a variable Herz-type Hardy space by using the atomic decomposition.
openaire   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Fractional integral operators involving a general class of polynomials [PDF]

, 1990
In the present paper the authors derive a number of interesting expressions for the composition of certain multidimensional fractional integral operators involving a general class of polynomials with essentially arbitrary coefficients.
Jain, R.M, Goyal, S.P, Srivastava, H.M
core   +1 more source

A Remark on Certain Integral Operators of Fractional Type [PDF]

Canadian Mathematical Bulletin, 2018
AbstractFor m, n ∈ , 1 < m ≤ n, we write n = n1 + … + nm where {n1 , … , nm} ⊂ . Let A1 , . . . , Am be n × n singular real matrices such thatwhere = {x : Ajx = 0}, dim() = n – nj, and A1 + … + Am is invertible. In this paper we study integral operators of the formn1 + … + nm = n, , 0 < r < 1, and the matrices Ai’s are as above. We obtain the
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source