Results 111 to 120 of about 3,730 (264)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Hermite-Hadamard Type Inequalities for Quasi-Convex Functions via Katugampola Fractional Integrals

International Journal of Analysis and Applications, 2018
The paper deals with quasi-convex functions, Katugampola fractional integrals and Hermite-Hadamard type integral inequalities. The main idea of this paper is to present new Hermite-Hadamard type inequalities for quasi-convex functions using Katugampola ...
Erhan Set, Ilker Mumcu
doaj   +2 more sources

Mittag–Leffler Fractional Stochastic Integrals and Processes with Applications

Mathematics
We study Mittag–Leffler (ML) fractional integrals involved in the solution processes of a system of coupled fractional stochastic differential equations.
Enrica Pirozzi
doaj   +1 more source

Hermite-Hadamard type inequalities for fractional integrals via Green's function. [PDF]

J Inequal Appl, 2018
Adil Khan M, Iqbal A, Suleman M, Chu YM.
europepmc   +1 more source

Some generalized integral inequalities via fractional integrals

, 2020
Summary: The main goal of this paper is to introduce a new integral definition concerned with the fractional calculus. Then we establish generalized Hermite-Hadamard type integral inequalities for convex functions using the proposed fractional integrals. The results presented provide extensions of those given in earlier works.
Sarıkaya, Mehmet Zeki, Budak, Hüseyin, Usta, Fuat   +2 more
openaire   +3 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Discussion of some inequalities via fractional integrals. [PDF]

J Inequal Appl, 2018
Kirane M, Samet B.
europepmc   +1 more source

Fractional Integral Inequalities via Hadamard’s Fractional Integral [PDF]

, 2017
Bashir Ahmad, Ahmed Alsaedi, Sotiris K. Ntouyas, Jessada Tariboon   +3 more
openaire   +1 more source

On Weighted Fractional Integral Inequalities

Journal of Functional Analysis, 2001
The author studies weighted positivity of a fractional power \((-\Delta)^\lambda\) of the Laplace operator, the weight function being the fundamental solution of this fractional power. Let \[ f(n,\lambda)=\psi\left(\frac{n}{2}\right)-\psi\left(\frac{n}{2}-\lambda\right)- \psi(\lambda) +\psi(1).
openaire   +2 more sources