Results 141 to 150 of about 6,726 (311)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Hermite-Hadamard's inequalities for fractional integrals and related fractional inequalities

, 2013
SET, ERHAN/0000-0003-1364-5396WOS: 000317262100039In the present note, first we have established Hermite-Hadamard's inequalities for fractional integrals.
Başak, Nagihan, Sarıkaya, Mehmet Zeki, Set, Erhan, Yaldız, Hatice   +3 more
core   +1 more source

Hermite-Hadamard type inequalities for fractional integrals via Green's function. [PDF]

J Inequal Appl, 2018
Adil Khan M, Iqbal A, Suleman M, Chu YM.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Montgomery identities for fractional integrals and related fractional inequalities

, 2009
In the present work we develop some integral identities and inequalities for the fractional integral. We have obtained Montgomery identities for fractional integrals and a generalization for double fractional integrals.
Moftakharzadeh, F., Anastassiou, G., Ghasemi, A., Hooshmandasl, M. R.   +3 more
core  

Discussion of some inequalities via fractional integrals. [PDF]

J Inequal Appl, 2018
Kirane M, Samet B.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Mittag–Leffler Fractional Stochastic Integrals and Processes with Applications

Mathematics
We study Mittag–Leffler (ML) fractional integrals involved in the solution processes of a system of coupled fractional stochastic differential equations.
Enrica Pirozzi
doaj   +1 more source

Hermite-Hadamard type inequalities for F-convex function involving fractional integrals. [PDF]

J Inequal Appl, 2018
Mohammed PO, Mohammed PO, Sarikaya MZ.
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source