Results 91 to 100 of about 239,946 (299)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Testing Fractional Inflation Persistence in the West African Monetary Zone

Buletin Ekonomi Moneter dan Perbankan
Understanding inflation persistence is of utmost significance for monetary policymakers in an era of heightened global economic interdependence and increased susceptibility to external shocks.
Afees Salisu, Nuruddeen Usman, Godday Ebuh   +2 more
doaj   +1 more source

New fractional integral unifying six existing fractional integrals

, 2016
Preprint submitted for ...
openaire   +2 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

A New Fractional Integration Operational Matrix of Chebyshev Wavelets in Fractional Delay Systems

Fractal and Fractional, 2019
Fractional integration operational matrix of Chebyshev wavelets based on the Riemann−Liouville fractional integral operator is derived directly from Chebyshev wavelets for the first time.
Iman Malmir
doaj   +1 more source

Fractional fundamental lemma and fractional integration by parts formula -- Applications to critical points of Bolza functionals and to linear boundary value problems

, 2015
In the first part of the paper, we prove a fractional fundamental (du Bois-Reymond) lemma and a fractional variant of the integration by parts formula. The proof of the second result is based on an integral representation of functions possessing Riemann ...
Bourdin, Loïc, Idczak, Dariusz
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Persistence in carbon footprint emissions: an overview of 92 countries

Carbon Management, 2019
The existing studies on persistence of ecological footprint have largely concentrated on the aggregate ecological footprint without adequately considering its components.
Sakiru Adebola Solarin, Luis A. Gil-Alana, Carmen Lafuente   +2 more
doaj   +1 more source

Trends in road accidents on Brazil's highways: Evidence of persistence using fractional integration. [PDF]

PLoS One, 2023
Wanke P, Gil-Alana LA, Tan Y.
europepmc   +1 more source