Results 111 to 120 of about 239,946 (299)

THE LONG MEMORY STORY OF REAL INTEREST RATES. CAN IT BE SUPPORTED? [PDF]

open access: yes
This papers finds evidence of fractional integration for a number of monthly ex post real interest rate series using the GPH semiparametric estimator on data from fourteen European countries and the US.
Agustín Duarte   +2 more
core  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

A three-dimensional wavelet based multifractal method : about the need of revisiting the multifractal description of turbulence dissipation data

open access: yes, 2003
We generalize the wavelet transform modulus maxima (WTMM) method to multifractal analysis of 3D random fields. This method is calibrated on synthetic 3D monofractal fractional Brownian fields and on 3D multifractal singular cascade measures as well as ...
Arneodo, Alain, Kestener, Pierre
core   +3 more sources

Fractional integrals of generalized functions [PDF]

open access: yesJournal of the Australian Mathematical Society, 1972
The concept of integrals of fractional order of a function f, defined by if Reα > 0, can be extended to generalised functions in the framework of the theory of convolution of distributions. The resulting theory [2, Chap. I §5.5] is very satisfactory for many purposes but there are circumstances in which it is not suitable.
openaire   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Realization of fractional order controllers [PDF]

open access: yesActa Montanistica Slovaca, 2003
An approach to realizations of fractional-order controllers is presented. The suggested approach is based on the use of continued fraction expansions.
O’Leary Paul   +5 more
doaj  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy