Results 121 to 130 of about 238,951 (299)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Geometric and Physical Interpretation of Fractional Integration and Fractional Differentiation

open access: yes, 2001
A solution to the more than 300-years old problem of geometric and physical interpretation of fractional integration and differentiation (i.e., integration and differentiation of an arbitrary real order) is suggested for the Riemann-Liouville fractional ...
Podlubny, Igor
core   +2 more sources

Some Integral Inequalities for Local Fractional Integrals

open access: yesInternational Journal of Analysis and Applications, 2017
In this paper, firstly we extend some generalization of the Hermite-Hadamard inequality and Bullen inequality to generalized convex functions. Then, we give some important integral inequalities related to these inequalities.
Sarikayala, M. Zeki   +2 more
openaire   +5 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Some fractional integral formulas for the Mittag-Leffler type function with four parameters

open access: yesOpen Mathematics, 2015
In this paper we present some results from the theory of fractional integration operators (of Marichev- Saigo-Maeda type) involving the Mittag-Leffler type function with four parameters ζ , γ, Eμ, ν[z] which has been recently introduced by Garg et al ...
Agarwal Praveen, Nieto Juan J.
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Daily Emissions of CO2 in the World: A Fractional Integration Approach

open access: yesEconometrics
In this article, daily CO2 emissions for the years 2019–2022 are examined using fractional integration for Brazil, China, EU-27 (and the UK), India, and the USA.
Luis Alberiko Gil-Alana, Carlos Poza
doaj   +1 more source

Accelerating the calibration of stochastic volatility models [PDF]

open access: yes
This paper compares the performance of three methods for pricing vanilla options in models with known characteristic function: (1) Direct integration, (2) Fast Fourier Transform (FFT), (3) Fractional FFT. The most important application of this comparison
Kilin, Fiodar
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Inequalities for Laguerre functions

open access: yesJournal of Inequalities and Applications, 1997
The main published inequality for Laguerre functions seems to be for Laguerre polynomials only; it is [2: 10.18(3)]: This paper presents several inequalities for Laguerre polynomials and Laguerre functions , most of which do not seem to be in the ...
Love ER
doaj  

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