Results 91 to 100 of about 473,820 (257)

On the Solvability of Caputo -Fractional Boundary Value Problem Involving -Laplacian Operator

open access: yesAbstract and Applied Analysis, 2013
We consider the model of a Caputo -fractional boundary value problem involving -Laplacian operator. By using the Banach contraction mapping principle, we prove that, under some conditions, the suggested model of the Caputo -fractional boundary value ...
Hüseyin Aktuğlu, Mehmet Ali Özarslan
doaj   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

open access: yesAdvanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong   +5 more
wiley   +1 more source

Uncertainty‐Guided Selective Adaptation Enables Cross‐Platform Predictive Fluorescence Microscopy

open access: yesAdvanced Intelligent Discovery, EarlyView.
Deep learning models often fail when transferred to new microscopes. A novel framework overcomes this by selectively adapting the early layers governing low‐level image statistics, while freezing deep layers that encode morphology. This uncertainty‐guided approach enables robust, label‐free virtual staining across diverse systems, democratizing ...
Kai‐Wen K. Yang   +9 more
wiley   +1 more source

Fractional p-Laplacian evolution equations

open access: yesJournal de Mathématiques Pures et Appliquées, 2016
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Mazón, José M.   +2 more
openaire   +1 more source

Quasi-optimal convergence rate for an adaptive method for the integral fractional Laplacian [PDF]

open access: yesMathematics of Computation, 2019
For the discretization of the integral fractional Laplacian $(-\Delta)^s$, $0 < s < 1$, based on piecewise linear functions, we present and analyze a reliable weighted residual a posteriori error estimator.
M. Faustmann, J. Melenk, D. Praetorius
semanticscholar   +1 more source

VALIANT: A Vision‐Authenticity Language Framework Through Integrated Experts and Aligned Numerical‐Textual Descriptors for Citri Reticulatae Pericarpium

open access: yesAdvanced Intelligent Systems, EarlyView.
Visual features, numerical descriptors, and controlled textual attributes extracted from smartphone images of Chenpi are integrated by VALIANT, a tailored multimodal framework for simultaneous storage‐age classification and authenticity verification. The workflow distinguishes genuine products from suspicious standard operating procedure mimics while ...
Simon C. K. Chan   +5 more
wiley   +1 more source

Non-Nehari Manifold Method for Fractional p-Laplacian Equation with a Sign-Changing Nonlinearity

open access: yesJournal of Function Spaces, 2018
We consider the following fractional p-Laplacian equation: -Δpαu+V(x)up-2u=f(x,u)-Γ(x)uq-2u,  x∈RN, where N≥2, pα⁎>q>p≥2, α∈(0,1), -Δpα is the fractional p-Laplacian, and Γ∈L∞(RN) and Γ(x)≥0 for a.e. x∈RN. f has the subcritical growth but higher than Γ(x)
Huxiao Luo, Shengjun Li, Wenfeng He
doaj   +1 more source

Model‐informed drug development to support nemolizumab clinical development in adults and adolescents with moderate to severe atopic dermatitis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Population pharmacokinetic (popPK) and pharmacokinetic‐pharmacodynamic (PK/PD) models were developed to support clinical development of nemolizumab, a humanized monoclonal antibody targeting the IL‐31 receptor α, in adolescents and adults with moderate‐to‐severe atopic dermatitis (AD).
Floris Fauchet   +17 more
wiley   +1 more source

Variational Inequalities for the Fractional Laplacian [PDF]

open access: yesPotential Analysis, 2016
19 ...
MUSINA, Roberta   +2 more
openaire   +4 more sources

Pharmacokinetics and pharmacodynamics of intravenous and oral (S)‐ketamine: Investigating metabolite contribution to subjective effects

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Oral administration of (S)‐ketamine for treatment‐resistant depression (TRD), as alternative to the registered intranasal or off‐label intravenous administrations, has high potential. However, it is characterized by an extensive first‐pass metabolism, resulting in low (S)‐ketamine exposure and high levels of active metabolites, including (S ...
Marije E. Otto   +5 more
wiley   +1 more source

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