Results 121 to 130 of about 61,286 (267)
Advanced Biology, EarlyView.The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li +10 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.This study investigates the bond quality of co‐extruded aluminum–titanium hybrid profiles, focusing on the lateral angular co‐extrusion (LACE) process. It examines how heat treatments (HT) affect intermetallic phase formation, bond strength, and material properties.
Norman Mohnfeld +9 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley +1 more source
Deformation Behavior of La2O3‐Doped Copper during Equal Channel Angular Pressing
Advanced Engineering Materials, EarlyView.By additions of strengthening elements and/or structure optimization, the mechanical properties of copper can be increased while keeping favorable electric conductivity. By combining addition of La2O3 and processing by equal channel angular pressing, substructure development is achieved, leading to increase in microhardness to more than double the ...
Lenka Kunčická +2 more
wiley +1 more source
Low‐Activation Compositionally Complex Alloys for Advanced Nuclear Applications—A Review
Advanced Engineering Materials, EarlyView.Low‐activation compositionally complex alloys (LACCAs) are advanced metallic materials primarily composed of low‐activation elements, offering advantages such as rapid compliance with operational standards and safe recyclability. This review highlights their potential for extreme high‐temperature irradiation environments as structural materials for ...
Yangfan Wang +8 more
wiley +1 more source
Multiscale Modeling of Process‐Induced Defects in Fused Filament Fabrication‐Printed Materials
Advanced Engineering Materials, EarlyView.This study presents a predictive multiscale modeling tool for defect analysis of fused filament fabricated‐printed materials and their performance prediction using a mechanistic data science‐based reduced‐order modeling approach. Process‐induced defects are inherent to additively manufactured parts and significantly influence the performance of printed
Satyajit Mojumder +3 more
wiley +1 more source
Direct Consolidation of Copper–Graphene Composite by Rotary Swaging
Advanced Engineering Materials, EarlyView.The applicability of the rotary swaging method for preparation of electroconductive copper–graphene composite by direct consolidation of powders is proven. The consolidated material features advantageous microstructure featuring fine grains and twins, with homogeneous distribution of graphene, primarily along the twin boundaries, which contribute to ...
Radim Kocich +2 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.Phase diagrams of transition‐metal di‐pnictides have been efficiently and quickly explored by combinatorial deposition of transition‐metal films and subsequent antimonization enabling the study of compounds with volatile elements. In (Fe,Ni)Sb2 and the (Fe,Cr)Sb2 substitution series, phase separation has been evidenced between class‐A and B marcasites ...
Martin Kostka +8 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.The share of technical thermoplastics is expected to grow further in the e‐mobility segment. In this study, a detailed temperature‐based tribological characterization of technical thermoplastics is performed. The tribological properties are discussed in terms of the dynamic mechanical properties of polymers at different ambient temperatures. A proof of
Harsha Raghuram +2 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.Primary phases and a fatigue crack are studied in a forged blank of an aluminum alloy using synchrotron and laboratory X‐ray computed tomography. To image the crack, the fatigue test is interrupted, and a static tensile load is applied to open the crack.
Jakob Schröder +6 more
wiley +1 more source