Results 21 to 30 of about 155,102 (233)

Fractional Moments on Bandit Problems

, 2012
Reinforcement learning addresses the dilemma between exploration to find profitable actions and exploitation to act according to the best observations already made. Bandit problems are one such class of problems in stateless environments that represent this explore/exploit situation.
B, Ananda Narayanan, Ravindran, Balaraman   +1 more
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Supersymmetric Relations Among Electromagnetic Dipole Operators

, 2001
Supersymmetric contributions to all leptonic electromagnetic dipole operators have essentially identical diagramatic structure. With approximate slepton universality this allows the muon anomalous magnetic moment to be related to the electron electric ...
A. Bartl, A. Czarnecki, D.F. Carvalho, E. Commins, E. Franco, E.A. Baltz, F. Borzumati, F. del Aguila, F. Gabbiani, H. Baer, H.N. Brown, J. Donoghue, J. Ellis, J. Ellis, J. Ellis, J. Frere, J. Gerard, J. Hisano, J. Polchinski, J.A. Grifols, Jonathan L. Feng, K. Cheung, K.W. Edwards, Kiwoon Choi, Lisa Everett, M. Brhlik, M. Carena, M. Duncan, M.L. Brooks, Michael Graesser, R. Arnowitt, R. Barbieri, S. Abel, S. Ahmed, S. Dimopoulos, S. Komine, Scott Thomas, Shinji Komine, Stephen P. Martin, T. Ibrahim, T. Ibrahim, T. Ibrahim, T. Ibrahim, T. Ibrahim, T. Ibrahim, T. Moroi, T. Moroi, Tarek Ibrahim, Utpal Chattopadhyay, W. Bernreuther, W. Buchmuller   +50 more
core   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

A Necessary Moment Condition for the Fractional Functional Central Limit Theorem [PDF]

We discuss the moment condition for the fractional functional central limit theorem (FCLT) for partial sums of x(t)=Δ^(-d)u(t), where d є (-1/2,1/2) is the fractional integration parameter and u(t) is weakly dependent.
Morten Ørregaard Nielsen, Søren Johansen   +1 more
core   +3 more sources

Generalized Widder Theorem via fractional moments

Journal of Functional Analysis, 2009
We provide a necessary and sufficient condition for the representability of a function as the classical multidimensional Laplace transform, when the support of the representing measure is contained in some generalized semi-algebraic set. This is done by employing a method of Putinar and Vasilescu [Putinar, M.
openaire   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Odd moments and adding fractions

Proceedings of the London Mathematical Society
AbstractWe prove near‐optimal upper bounds for the odd moments of the distribution of coprime residues in short intervals, confirming a conjecture of Montgomery and Vaughan. As an application, we prove near‐optimal upper bounds for the average of the refined singular series in the Hardy–Littlewood conjectures concerning the number of prime ‐tuples for
Thomas F. Bloom, Vivian Kuperberg
openaire   +4 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source