Results 181 to 190 of about 24,943,460 (295)

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub   +3 more
wiley   +1 more source

Quadrature solution of fractional coupled burgers and plankton-oxygen dynamics under climate change. [PDF]

open access: yesSci Rep
Zayed MA   +6 more
europepmc   +1 more source

One‐Pot Synthesis of a Small Synthetic Ligand for Antibody Purification

open access: yesBiotechnology and Bioengineering, EarlyView.
One‐pot liquid‐phase synthesis of the synthetic ligand B1Al2A2 enables controllable ligand density and efficient capture of IgG and IgY with high recovery and purity, streamlining small‐ligand affinity purification workflows. ABSTRACT The development of synthetic affinity ligands offers a cost‐effective alternative to traditional biological ligands ...
Carolina Mota Natal   +8 more
wiley   +1 more source

Microfiltration (MF) and Ultrafiltration (UF) for Sewage and Surface Water Concentration for SARS‐CoV‐2 and Other Enveloped Viruses' Detection in Wastewater‐Based Epidemiology (WBE)

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT This study objective was to evaluate hollow fiber membranes for concentration of enveloped enteric viruses in sewage and surface water samples. Microfiltration (MF, 0.2 µm nominal pore size) and ultrafiltration (UF, 100 kDa molecular weight cut‐off) hollow fiber membranes were compared for the concentration of the bovine respiratory syncytial ...
Rodrigo Almeria Ragio   +3 more
wiley   +1 more source

Quercetin‐zinc coordination polymer coated CaCO3 nanoparticles potentiate radiotherapy through reprogramming tumor immunosuppression

open access: yesBMEMat, EarlyView.
Synthesis of QZCaCO3‐PEG to synergistically enhance the immunogenicity of radiotherapy through concurrent Zn2+‐induced cancer cell pyroptosis and Que‐mediated hypoxia amelioration through sequentially suppressing TGF‐β secretion and ECM deposition. Abstract Radiotherapy has demonstrated broad applications in treating solid tumors, but the hostile tumor
Chunjie Wang   +9 more
wiley   +1 more source

Interaction of Operator−Patient Sex on Peri‐Procedural Treatments and Major Coronary Outcomes After Percutaneous Coronary Intervention

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background There are limited data evaluating the association between operator−patient sex, and outcomes in patients undergoing percutaneous coronary intervention (PCI). Methods We included 138,112 consecutive PCI procedures in patients presenting with acute coronary syndrome (ACS) in England and Wales, 2017−2020.
Sharon A. Ayayo   +6 more
wiley   +1 more source

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