Results 61 to 70 of about 9,859,885 (301)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Quantum-metric-induced quantum Hall conductance inversion and reentrant transition in fractional Chern insulators

Physical Review Research
The quantum metric of single-particle wave functions in topological flat bands plays a crucial role in determining the stability of fractional Chern insulating (FCI) states.
Ang-Kun Wu, Siddhartha Sarkar, Xiaohan Wan, Kai Sun, Shi-Zeng Lin   +4 more
doaj   +1 more source

Interval Shannon Wavelet Collocation Method for Fractional Fokker-Planck Equation

Advances in Mathematical Physics, 2013
Metzler et al. introduced a fractional Fokker-Planck equation (FFPE) describing a subdiffusive behavior of a particle under the combined influence of external nonlinear force field and a Boltzmann thermal heat bath.
Shu-Li Mei, De-Hai Zhu
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Uniqueness of Landau levels and their analogs with higher Chern numbers

Physical Review Research
Landau levels are the eigenstates of a charged particle in two dimensions under a magnetic field and are at the heart of the integer and fractional quantum Hall effects, which are two prototypical phenomena showing topological features.
Bruno Mera, Tomoki Ozawa
doaj   +1 more source

Analysis of mathematical models for description of the fractional composition of disperse elastic fillers

Российский технологический журнал, 2019
The paper presents a comparative analysis of integral and differential mathematical models describing the particle size distribution of dispersed elastic fillers. Crushed vulcanizates obtained by high temperature shear grinding were studied as objects of
Yu. A. Naumova, I. V. Gordeeva
doaj   +1 more source

Arctic marine secondary organic aerosol contributes significantly to summertime particle size distributions in the Canadian Arctic Archipelago [PDF]

Atmospheric Chemistry and Physics, 2019
Summertime Arctic aerosol size distributions are strongly controlled by natural regional emissions. Within this context, we use a chemical transport model with size-resolved aerosol microphysics (GEOS-Chem-TOMAS) to interpret measurements of aerosol size
B. Croft, R. V. Martin, R. V. Martin, W. R. Leaitch, J. Burkart, J. Burkart, R. Y.-W. Chang, D. B. Collins, D. B. Collins, P. L. Hayes, A. L. Hodshire, L. Huang, J. K. Kodros, J. K. Kodros, A. Moravek, E. L. Mungall, J. G. Murphy, S. Sharma, S. Tremblay, G. R. Wentworth, G. R. Wentworth, M. D. Willis, M. D. Willis, J. P. D. Abbatt, J. R. Pierce   +24 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Non-Integer order calculation applied in Quantum Mechanics: Particle in a one-dimensional finite well

Nova Scientia
Fractional calculus is becoming increasingly important nowadays in studying and understanding fundamental physical phenomena, both simple and complex, through the formulation of generalized models.
Joel Elías Escudero-Gómez, Ernesto Alejandro Mendoza Álvarez, Guillermo Fernández Anaya, José Job Flores-Godoy , Leo Diago Cisneros   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source