Results 211 to 220 of about 1,185,445 (242)

Subtype-specific secretion of extracellular vesicles by LRRK2 and Rab GTPases under lysosomal stress. [PDF]

iScience
Sakurai M, Kuwahara T, Suenaga S, Takatori S, Tomita T, Shalit T, Tengstrand E, Hsieh F, Iwatsubo T.   +8 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Bioactive Peptides from Andean Crops: Lactic Acid Bacteria Fermentation, Complementary Proteolysis, and Biological Activities. [PDF]

Foods
Barba-Ostria C, Barreno-Sánchez MJ, Salazar-Garcés LF, Guamán-Bautista J, Guamán LP, Guamán LP.   +5 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Effect of phosphorus fraction in shaping bacterial and archaeal community succession in the largest hydrologically connected lake of Northeast Asia. [PDF]

Front Microbiol
Xie Z, Liu X, Bo B, Wei W, Li C, Ye C.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Enhanced In Vivo Antinociceptive Activity and GC-MS Chemical Profiling of In Vitro-Grown <i>Acmella radicans</i> Plants Elicited with <i>Rhizopus microsporus</i>. [PDF]

Molecules
Hernández-Aubert G, Montiel-Ruiz RM, Hurtado-Díaz I, Silva-Guzmán JA, Torres-Rendón JG, Manríquez-González R, Cruz-Sosa F, Bernabé-Antonio A.   +7 more
europepmc   +1 more source

From Validation to Clinical Interpretation: A Flow Cytometric Th17-Cell Assay for STAT1- and STAT3-Related Inborn Errors of Immunity. [PDF]

Scand J Immunol
Toft MJ, Sørensen CD, Christiansen M, Larsen CS, Holm M, Nedergaard D, Hansen R, Egedal LH, Staunstrup NH, Møller BK, Petersen MS, Jensen JMB.   +11 more
europepmc   +1 more source

Acetogenins from <i>Annona coriacea</i> Target TNFR1-Mediated Cell Death in Head and Neck Cancer. [PDF]

ACS Omega
Cordeiro GAR, Oliveira AGS, Junqueira JGM, Raspanti Sousa L, da Silva Gonçalves A, Asevedo EA, Ribeiro REM, Reis R, Pasqualotto Severino VG, Thomé RG, Dos Santos HB, Ribeiro RIMA.   +11 more
europepmc   +1 more source

Fluorine Transformation Along the Chain from Phosphate Rock to Phosphogypsum and Phosphogypsum-Based Cemented Backfill. [PDF]

Materials (Basel)
Zhou Y, Shi Y, Min C, Zhu Q.
europepmc   +1 more source