Results 201 to 210 of about 47,313 (242)

Incidence of Major Adverse Cardiovascular Events in Patients With Rheumatoid Arthritis Treated With JAK Inhibitors Compared With Biologic Disease‐Modifying Antirheumatic Drugs: Data From an International Collaboration of Registries

Arthritis &Rheumatology, EarlyView.
Objective Our objective was to assess the incidence of major adverse cardiovascular events (MACEs) in patients with rheumatoid arthritis (RA) treated with JAK inhibitors (JAKi), tumor necrosis factor inhibitors (TNFi), or biologic disease‐modifying antirheumatic drugs with other modes of action (bDMARD‐OMA) in a multicountry, real‐world population ...
Romain Aymon, Denis Mongin, Romain Guemara, Zubeyir Salis, Johan Askling, Denis Choquette, Catalin Codreanu, Daniela Di Giuseppe, Irini Flouri, Doreen Huschek, Kimme L. Hyrich, Florenzo Iannone, Tore K. Kvien, Burkhard F. Leeb, Dan Nordström, Lucia Otero‐Varela, Karel Pavelka, Manuel Pombo‐Suarez, Ana Rodrigues, Ziga Rotar, Prodromos Sidiropoulos, Sella A. Provan, Anja Strangfeld, Trokovic Nina, Jakub Zavada, Lianne Kearsley‐Fleet, Delphine S. Courvoisier, Axel Finckh, Kim Lauper   +28 more
wiley   +1 more source

Efficacy and safety of dotinurad versus febuxostat for the treatment of gout: a randomised, multicentre, double‐blind, phase 3 trial in China

Arthritis &Rheumatology, Accepted Article.
Objectives Dotinurad is a selective urate reabsorption inhibitor that reduces serum urate levels. We compared the efficacy and safety of dotinurad with febuxostat in Chinese patients with gout. Methods This phase 3, multicentre, randomised, double‐blind, parallel‐group study randomly allocated (1:1) eligible patients with gout to receive oral dotinurad
Jia Sun, Yu Wang, Yongjing Cheng, Dongmei Guo, Jiankang Hu, Dongzhou Liu, Zhengnan Gao, Changgui Li, Yibing Lu, Xiaodan Kong, Yu Liu, Zhenyu Jiang, Bin Yi, Hongfeng Zhang, Baijie Xu, Shihao Yu, Rieko Kokan, Kohei Ishikawa, Mikiko Kawakatsu, Zhuoli Zhang   +19 more
wiley   +1 more source

Trans-styloid fixation of fractures of the distal radius: A prospective randomized comparison between 6- and 1 -week postoperative immobilization in 60 fractures

, 1999
Jérôme Allain, Pierre le Guilloux, S. Le Mouël, D Goutallier   +3 more
openalex   +1 more source

First‐in‐human safety, tolerability, pharmacokinetics and pilot food‐effect study of the candidate antimalarial compound MMV367

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To evaluate the safety, tolerability and pharmacokinetics in healthy participants of orally administered MMV367 (GSK3772701), a novel antimalarial interfering with Plasmodium falciparum acyl coenzyme A synthetase 10/11 function. Methods This first‐in‐human study enrolled 47 healthy male and female participants.
Andrea Kuemmerle, Nand Singh, Denis Gossen, Annick Janin, Raman Sharma, Anthony Cahn, Rachel A. Gibson, Somasekhara R. Menakuru, Erin Lambourne, Tom Dove, Francisco‐Javier Gamo, Laura Sanz, Benoit Bestgen, Stephan Chalon   +13 more
wiley   +1 more source

External Fixation for Supracondylar Fracture in Children.

, 1999
Naoaki Kahara, Hiroo Fujiwara, Meguru Inoue, K Tsunashima, Takashi Maehara, Atsushi Inoue   +5 more
openalex   +2 more sources

Sacrificial strategy towards the formation of vascular‐like networks in volumetric tissue constructs

BMEMat, EarlyView.
This mini‐review highlights the latest progress in the sacrificial template‐enabled creation of patent vascular‐like networks, which can be incorporated into volumetric tissue constructs. Such microchannel networks can provide an immediate supply of nutrition and O2 to those cells residing next to the channels.
Christian Buckley, Rana Ibrahim, Felicia Giordano, Nuo Xu, Brandon Sems, Hongjun Wang   +5 more
wiley   +1 more source

Localized EIS Data for Capacity and SOH Prediction With Neural Networks

Battery Energy, EarlyView.
This study showed a higher accurate capacity and state of health predictions using solely the most correlated frequencies for a neural network model. Findings showed that the charge transfer region is essential for battery prognosis studies, reducing the time needed for battery characterization using impedance.
Hakeem Thomas, Mark H. Weatherspoon, Ruben Nelson   +2 more
wiley   +1 more source

External Fixation for Bennett's Fracture and Rolando's Fracture.

, 1999
Tatsuro Tanaka, Yasuo Hayashi, Hiroaki Tanaka, Shin Fukuyama, Hiroshi Kinuhara, Manabu Tanoue, Tetsuhiro Ooyama, Takeshi Yamashita, Shinichi Nakashima   +8 more
openalex   +2 more sources

Transfer Learning‐Based Data‐Fusion Model Framework for State of Health Estimation of Power Battery Packs

Battery Energy, EarlyView.
To handle nonlinearity and feature coupling, a data‐driven aging model is proposed, employing dual Gaussian Process Regressions and transfer learning to enhance model efficiency and accuracy. Adaptive filtering refines the model by integrating aging features and output capacity, resulting in a closed‐loop data fusion framework for SOH estimation ...
Zhiqiang Lyu, Xinyuan Wei, Longxing Wu, Chunhui Liu   +3 more
wiley   +1 more source

Minimizing batch‐to‐batch variability of a live virus vaccine by process analytical technologies

Biotechnology Progress, EarlyView.
Abstract For bioprocesses producing live virus, such as enterovirus Coxsackievirus A21, viral titer (infectivity basis) decay rates can exceed 30% within a day. Consequently, harvest timing is paramount. To optimize titer at harvest, a continuous viral product titer model was generated to elucidate kinetics.
Katherine Forrester, Thomas R. Blanda, Marena Trauger, Rachel Thompson, Neil Templeton   +4 more
wiley   +1 more source