Results 201 to 210 of about 125,598 (296)

Evaluation of Comminuted Fractures of the Distal End of the Radius Treated by External Fixation.

open access: bronze, 1993
Mamoru Kitagawa   +6 more
openalex   +2 more sources

Mechanical Stretch‐Induced Interlayer Coordination between MMP2 and COL17A1 Exacerbates Regenerative Exhaustion in Skin

open access: yesAdvanced Science, EarlyView.
Regeneration reaches a hidden limit under mechanical stretch. Prolonged tension alters dermal–epidermal communication, exhausting epidermal stem cells via MMP2–COL17A1 signaling. MMP2 inhibition by Marimastat preserves adhesion and regenerative capacity, offering a potential strategy to overcome the inherent boundaries of skin expansion.
Yidan Sun   +13 more
wiley   +1 more source

Cost-Effectiveness of Locking vs Nonlocking Plates for Ankle Fracture Fixation: A Retrospective PROMIS-Based Cohort Study. [PDF]

open access: yesFoot Ankle Orthop
Balu AR   +6 more
europepmc   +1 more source

Polo‐Like Kinase 1 Phosphorylation Tunes the Functional Viscoelastic Properties of the Centrosome Scaffold

open access: yesAdvanced Science, EarlyView.
To enable mitotic spindle assembly during cell division, centrosomes must bear tensile stresses generated by microtubule‐mediated pulling forces. Micro‐rheology reveals that PLK‐1 phosphorylation of the scaffold protein SPD‐5 tunes the viscoelasticity, size, and morphology of the centrosome scaffold in C. elegans.
Matthew Amato   +5 more
wiley   +1 more source

Enhanced Selenium Supplement Extends Lifespan and Delays Multi‐Organs Aging by Regulating the Sik1 Pathway Through Maintaining Calcium Homeostasis

open access: yesAdvanced Science, EarlyView.
Aging involves physiological decline and heightened disease susceptibility, necessitating effective interventions. Redox‐responsive selenium‐loaded nanoparticles (SeMSNs) are developed, which delay cellular senescence by reducing oxidative stress and senescence markers (p16/p21). In aged mice, SeMSNs extend lifespan, improve organ function, and restore
Yang Yu   +15 more
wiley   +1 more source

Neuronal Endothelin a Receptor Mediates Experimental and Clinical Vascular Pain through an Endothelial‐Neural Axis

open access: yesAdvanced Science, EarlyView.
The authors develop mouse models by mimicking peripheral vascular diseases, combining multiple strategies and transgenic mouse lines, to demonstrate that ECs, but not macrophages or SMCs, play an active role mediated by endothelial ET‐1/neural ETAR signaling and beyond endothelial homeostatic angiocrine by driving protective pain through the ...
Zuo‐Jie Jiang   +28 more
wiley   +1 more source

Multifunctional Fluorescent Microgel‐Embedded Hydrogels for Temperature and X‐Ray Sensing

open access: yesAdvanced Science, EarlyView.
In this study, the application of a multifunctional fluorescent hydrogel based on AIE microgels, integrated with machine‐learning algorithms for the detection of temperature and X‐rays is prestented. This innovative platform not only simultaneously elevates temperature and X‐ray sensing performance but also preserves outstanding mechanical robustness ...
Hao Jiang   +11 more
wiley   +1 more source

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