Results 221 to 230 of about 1,616,224 (390)

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang   +12 more
wiley   +1 more source

FUNCTIONAL OUTCOME OF VOLAR LOCKING PLATE FIXATION IN ADULTS FOR DISPLACED INTRA ARTICULAR FRACTURE OF DISTAL RADIUS

open access: hybrid
Muhammad Aamir   +6 more
openalex   +2 more sources

Long term results of percutaneous fixation of proximal humerus fractures

open access: green, 2012
Christian Carulli   +5 more
openalex   +2 more sources

Infection after fracture fixation: Current surgical and microbiological concepts.

open access: yesInjury, 2016
W. Metsemakers   +7 more
semanticscholar   +1 more source

Predictors and Complications of Delayed Femoral Shaft Fracture Fixation in Pediatric Patients. [PDF]

open access: yesJ Pediatr Soc North Am
Ali S   +5 more
europepmc   +1 more source

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

open access: yesAdvanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló   +2 more
wiley   +1 more source

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