Results 101 to 110 of about 902,895 (307)

Computational simulation of bone fracture healing under inverse dynamization [PDF]

, 2017
Adaptive finite element models have allowed researchers to test hypothetical relationships between the local mechanical environment and the healing of bone fractures.
Epari, Devakara R., Schuetz, Michael A., Wilson, Cameron John   +2 more
core   +1 more source

Entropy‐Driven Design of Low‐Melting‐Point Alloys via Compositionally Complex Strategy

Advanced Engineering Materials, EarlyView.
Conventional low‐melting‐point alloys (LMPAs) are limited by a narrow compositional space and inherent property trade‐offs. This review presents an entropy‐driven design strategy that overcomes these limitations, ushering in a new class of low‐melting‐point compositionally complex alloys (LMCCAs).
Yinghui Shang, Jianxiang Zhao, Zhaoqi Chen, Hao Gong, Yinsen Yan, Junlei Tao, Yong Yang   +6 more
wiley   +1 more source

PRMT6 inhibitors promote fracture healing by modulating osteoclast glucose metabolism

Frontiers in Immunology
IntroductionImpaired fracture healing remains a significant clinical challenge due to the complexity of the healing process. Osteoclasts, derived from monocytes, are pivotal in bone tissue reconstruction, yet no effective clinical tools exist to promote ...
Nan Wu, Renkai Wang, Shensheng Nian, Hao Zhang, Panyu Zhou, Hao Tang   +5 more
doaj   +1 more source

Low‐dose TNF augments fracture healing in normal and osteoporotic bone by up‐regulating the innate immune response

EMBO Molecular Medicine, 2015
The mechanism by which trauma initiates healing remains unclear. Precise understanding of these events may define interventions for accelerating healing that could be translated to the clinical arena.
James K Chan, Graeme E Glass, Adel Ersek, Andrew Freidin, Garry A Williams, Kate Gowers, Ana I Espirito Santo, Rosemary Jeffery, William R Otto, Richard Poulsom, Marc Feldmann, Sara M Rankin, Nicole J Horwood, Jagdeep Nanchahal   +13 more
doaj   +1 more source

Simulation‐Based Analysis of Insert Pull‐Out in Nickel‐Polyurethane Hybrid Foams Using CT‐Derived Geometries

Advanced Engineering Materials, EarlyView.
CT‐based finite element simulations combined with in situ X‐ray computed tomography are used to analyze insert pull‐out in nickel‐coated polymer foams. Despite variations in material parameters, deformation consistently concentrates within a narrow annular region around the insert.
Yannik Bautz, Jonas Fell, Hendrik Jost, Stefan Diebels, Hans‐Georg Herrmann   +4 more
wiley   +1 more source

Fabrication Routes for Ionic Conducting Fiber Strain Sensors

Advanced Engineering Materials, EarlyView.
Ionic conducting fiber strain sensors (ICFSs) offer compliant, textile‐integrable sensing. Thus far, the commercialization of ICFSs has been constrained by fiber fabrication routes. This review provides a fabrication‐centric analysis of ICFSs correlating processing strategies with material properties and scalability.
Leo John Kershaw, Zhanhong Yang, Anne Ladegaard Skov, Magdalena Skowyra   +3 more
wiley   +1 more source

Influence of TiC and TiN Ceramic Reinforcements on the Microstructure, Thermal Expansion Behavior, and Tensile Properties of Invar 36 Manufactured by Laser Powder Bed Fusion

Advanced Engineering Materials, EarlyView.
This study examines Invar composites reinforced with titanium carbide (TiC) and titanium nitride (TiN) using laser powder bed fusion (LPBF). It presents the influence of reinforcements on microstructure, tensile properties, and thermal expansion. Results show that TiC effectively strengthens Invar while maintaining low thermal expansion, whereas TiN ...
Ayodeji Nathaniel Oyedeji, Natasha Sacks, Johannes Pötschke, Björn Matthey   +3 more
wiley   +1 more source

Autologous ADSCs with exogenous NPY promotes fracture healing in ovariectomized rats

Heliyon
Objective: To evaluate the role of autologous adipose-derived stem cells (ADSCs) with exogenous neuropeptide Y (NPY) on osteoporotic fracture healing. Methods: We established a fracture healing model in ovariectomized rats of osteoporosis.
Hong Liu, Jiaoyang Wu, Huixuan Wu, Ting Wang, Houde Zhou, Min Liu   +5 more
doaj   +1 more source

Zoledronic Acid in Reducing Clinical Fracture and Mortality after Hip Fracture.

, 2007
BACKGROUND: Mortality is increased after a hip fracture, and strategies that improve outcomes are needed. METHODS: In this randomized, double-blind, placebo-controlled trial, 1065 patients were assigned to receive yearly intravenous zoledronic acid (at a
Moore, K.A., Lyles, K.W., Boonen, S., Nordsletten, L., Abrams, K., Hodgson, P.K., Colón-Emeric, C.S., Recknor, C., Eriksen, E.F., Mesenbrink, P., Adachi, J.D., Pieper, C.F., Hyldstrup, L., Magaziner, J.S., Horowitz, Z., Orloff, J.J., Mautalen, C., Lavecchia, C., Zhang, J., for the HORIZON Recurrent Fracture, Trial   +19 more
core   +1 more source

Rapidly Solidified High‐Strength Invar 36 Prepared by Planar‐Flow Melt Spinning

Advanced Engineering Materials, EarlyView.
The Invar 36 alloy was rapidly solidified using the planar‐flow melt‐spinning technique. Ribbon samples with thicknesses ranging from 20 to 160 mm were produced. As the grain size of the ribbon decreased to sub‐micron levels, the hardness increased by more than 2 times.
Bekir Akgül, Mehmet Kul
wiley   +1 more source