Results 51 to 60 of about 105,053 (266)

Vibration therapy as an intervention for enhancing trochanteric hip fracture healing in elderly patients: a randomized double-blinded, placebo-controlled clinical trial

Trials, 2021
Background There are more than 300,000 hip fractures yearly in the USA with mortality rates of 20% within 1 year. The treatment of osteoporotic fractures is a major challenge as bone quality is poor, and healing is expected to delay due to the impaired ...
Ronald Man Yeung Wong, Simon Kwoon Ho Chow, Ning Tang, Yik Lok Chung, James Griffith, Wing Hong Liu, Raymond Wai Kit Ng, Chi Yin Tso, Wing Hoi Cheung   +8 more
doaj   +1 more source

Development of an ischemic fracture healing model in mice

Acta Orthopaedica, 2022
Background and purpose: In fracture healing, ischemia caused by vascular injuries, chronic vascular diseases, and metabolic comorbidities is one of the major risk factors for delayed union and non-union formation.
Maximilian M Menger, Janine Stutz, Sabrina Ehnert, Andreas K Nussler, Mika F Rollmann, Steven C Herath, Benedikt J Braun, Tim Pohlemann, Michael D Menger, Tina Histing   +9 more
doaj   +1 more source

Molecular factors involved in the development of diabetic foot syndrome [PDF]

, 2012
Diabetes is one of the major challenges of modern medicine, as it is considered a global epidemic of the XXI century. The disease often leads to the development of serious, health threatening complications.
Brun-Olszewska, Bożena, Olszewski, Paweł, Bruhn-Olszewska, Bożena, Węgrzyn, Alicja, Gabig-Cimińska, Magdalena, Korzon-Burakowska, Anna, Jakóbkiewicz-Banecka, Joanna   +6 more
core  

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Multiple targets identified with genome wide profiling of small RNA and mRNA expression are linked to fracture healing in mice

Bone Reports, 2021
Long-bone fracture is a common injury and its healing process at the fracture site involves several overlapping phases, including inflammation, migration of mesenchymal progenitors into the fracture site, endochondral ossification, angiogenesis and ...
Matthieu Bourgery, Erika Ekholm, Katja Fagerlund, Ari Hiltunen, Tero Puolakkainen, Juha-Pekka Pursiheimo, Terhi Heino, Jorma Määttä, Jussi Heinonen, Emrah Yatkin, Tiina Laitala, Anna-Marja Säämänen   +11 more
doaj   +1 more source

Associations of Sleep and Shift Work With Osteoarthritis Risk

Arthritis Care &Research, EarlyView.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik, Abigail Bridgeman, Erik D. Herzog, Vy Pham, Bradley A. Evanoff, Farshid Guilak   +5 more
wiley   +1 more source

Fracture testing of a self-healing polymer composite

, 2001
Inspired by biological systems in which damage triggers an autonomic healing response, we have developed a polymer composite materials that can heal itself when cracked. This paper summarizes the self-healing concept for polymeric composite materials and
Brown, Eric N., N. R. Sottos, White, Scott R., S. R. White, Sottos, Nancy R., E. N. Brown   +5 more
core   +1 more source

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

Arthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie, Timothy Beukelman, Nicholas P. McCormick, Jeffrey R. Curtis   +3 more
wiley   +1 more source

THE EFFECT OF DENERVATION ON FRACTURE HEALING , AN EXPERIMENTAL STUDY ON RABBITS [PDF]

Basrah Journal of Surgery, 2014
THE EFFECT OF DENERVATION ON FRACTURE HEALING , AN EXPERIMENTAL STUDY ON RABBITS Thamer A Hamdan , Mubder A Mohammed Saeed & Abbas Salman Ismael Abstract Many studies suggested a relation between denervation and fracture healing either in positive or ...
THAMIR A. HAMDAN, Mubder A Mohammed Saeed, Abbas Salman ISMAEL   +2 more
doaj   +1 more source

Effects of repeated intravenous doses of tranexamic acid on closed tibial fracture healing: Experimental study based on the rat model

, 2023
Objective: The aim of this study was to assess the effects of tranexamic acid on fracture healing in the rat tibia closed fracture model.Methods: Sixty-four male Sprague-Dawley rats were included in this study, where closed fracture and intramedullary ...
Doğan, İbrahim, Birişik, Fevzi, Erol Rustu Bozkurt, Kalyenci, Ahmet Sinan, Fevzi Birisik, Yucel Bilgin, Ahmet Sinan Kalyenci, Yusuf Ozturkmen, Bozkurt, Erol Rüstü, Ibrahim Dogan, Öztürkmen, Yusuf   +10 more
core   +1 more source