Results 31 to 40 of about 281,589 (315)

Use of Statins and Risk of Fractures [PDF]

Obstetrical and Gynecological Survey, 2001
Previous studies have reported lower fracture risks in patients taking 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins).To investigate risk of fracture among statin users.Case-control study of data from the General Practice Research Database (GPRD).A total of 683 general clinical practices in the United Kingdom.Cases were 81 880 ...
Van Staa, Tjeerd; id_orcid 0000-0001-9363-742X, van Staa, T P, Wegman, S, de Vries, F, Leufkens, B, Cooper, C   +5 more
openaire   +6 more sources

Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study [PDF]

, 2018
BackgroundGlucocorticoids are associated with increased fracture risk and are the mainstay of treatment in polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). However, fracture risk in these conditions has not been previously quantified. The aim
Mallen, Bucknall, Hider, Paskins, Roddy, Helliwell, Muller   +6 more
core   +1 more source

Trabecular bone score, bone mineral density and fracture risk in women with rheumatoid arthritis (pilot study)

Научно-практическая ревматология, 2023
The aim – to assess bone mineral density (BMD) and microarchitecture, as well as the risk of fractures in postmenopausal women with rheumatoid arthritis (RA).
M. V. Kozyreva, O. V. Dobrovolskaya, N. V. Demin, O. A. Nikitinskaya, N. V. Toroptsova   +4 more
doaj   +1 more source

Compromised bone strength in patients with alcoholic liver cirrhosis [PDF]

Medicinski Podmladak, 2020
Osteoporosis and/or osteopenia are frequently observed complications in alcoholic liver disease patients, especially in its irreversible stage (alcoholic liver cirrhosis - ALC).
Jadžić Jelena, Đonić Danijela
doaj   +1 more source

Fracture Risk and Risk Factors for Osteoporosis [PDF]

Deutsches Ärzteblatt international, 2015
As the population ages, diseases of the elderly are becoming more common, including osteoporosis. Ways to assess the risk of fracture and the distribution and effects of known risk factors for osteoporosis will be important in planning for future healthcare needs, as well as in the development of preventive strategies.The study population included 6029
Christian, Schürer, Henri, Wallaschofski, Matthias, Nauck, Henry, Völzke, Hans-Christof, Schober, Anke, Hannemann   +5 more
openaire   +2 more sources

RANK/RANKL/OPG pathway: genetic associations with stress fracture period prevalence in elite athletes [PDF]

, 2015
Context: The RANK/RANKL/OPG signalling pathway is important in the regulation of bone turnover, with single nucleotide polymorphisms (SNPs) in genes within this pathway associated with bone phenotypic adaptations.
Stellingwerff, Trent, Varley, Ian, Sale, C, Ranson, Craig, Greeves, JP, Ranson, C, Fraser, WD, Stellingwerff, T, Hughes, David C, Varley, I, Greeves, Julie P, Sale, Craig, Hughes, DC, Fraser, William D   +13 more
core   +1 more source

Epidemiology of Fractures and Assessment of Fracture Risk

Clinics in Laboratory Medicine, 2000
Osteoporosis is a common condition that is clinically important because of its association with fracture. Fracture risk is ultimately determined by the relation between bone strength and propensity to trauma. Bone density is a key determinant of bone strength, and depends on the bone gained during growth and consolidation, and the subsequent rate of ...
Black, D, Cooper, C
openaire   +3 more sources

Risk of Fracture with Thiazolidinediones: Disease or Drugs? [PDF]

Calcified Tissue International, 2012
The use of thiazolidinediones (TZDs) has been associated with an increased fracture risk. In addition, type 2 diabetes mellitus (T2DM) has been linked with fracture. We evaluated to what extent the association between TZD use and fracture risk is related to the drug or to the underlying disease.
Van Staa, Tjeerd; id_orcid 0000-0001-9363-742X, Bazelier, Marloes T, Vestergaard, Peter, Gallagher, Arlene M, van Staa, Tjeerd-Pieter, Cooper, Cyrus, Leufkens, Hubert G M, de Vries, Frank   +7 more
openaire   +7 more sources

Bone fractures after menopause [PDF]

, 2010
Every year 30% of individuals above age 65 fall, and falls are the principal cause of bone fractures. To reduce fracture incidence requires both prevention of falls and maintenance of bone strength.PubMed searches were performed, for studies of the ...
Ralston, Stuart H., J. L. Evers, Baird, D. T., A. Volpe, Ralston, S.H., Brandi, M.L., G. Benagiano, Brandi, Maria Luisa, S. H. Ralston, P.G. Crosignani, P. Bouchard, Rizzoli, R., ESHRE Capri Workshop Grp, Barlow, David H., La Vecchia, C., Negri, E., M. L. Brandi, P. G. Crosignani, Rizzoli, Rene, Benagiano, G., S. E. Papapoulos, Evers, J.L.H., D. H. Barlow, J. Collins, C. La Vecchia, Baird, D.T., Negri, Eva, Crosignani, P. G., Papapoulos, Socrates E., Glasier, A., R. Rizzoli, Barlow, D.H., A. Glasier, Vecchia, C. la, Collins, J., D. T. Baird, Volpe, A., Bouchard, P., Crosignani, P.G., Bouchard, Philippe, ?, ?, Papapoulos, S.E., E. Negri, Evers, J. L. H.   +43 more
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Zoledronic Acid in Reducing Clinical Fracture and Mortality after Hip Fracture. [PDF]

, 2007
BACKGROUND: Mortality is increased after a hip fracture, and strategies that improve outcomes are needed. METHODS: In this randomized, double-blind, placebo-controlled trial, 1065 patients were assigned to receive yearly intravenous zoledronic acid (at a
Moore, K.A., Lyles, K.W., Boonen, S., Nordsletten, L., Abrams, K., Hodgson, P.K., Colón-Emeric, C.S., Recknor, C., Eriksen, E.F., Mesenbrink, P., Adachi, J.D., Pieper, C.F., Hyldstrup, L., Magaziner, J.S., Horowitz, Z., Orloff, J.J., Mautalen, C., Lavecchia, C., Zhang, J., for the HORIZON Recurrent Fracture, Trial   +19 more
core   +1 more source