Results 1 to 10 of about 330,505 (173)

Fracture of an unnamed bone [PDF]

open access: yesEmergency Medicine Journal, 2007
A 28-year-old professional footballer presented to the emergency department having sustained an isolated direct kick to the left shin with …
Baldeep Bains, Keith Porter
openaire   +5 more sources

Simulating pharmaceutical treatment effects on osteoporosis via a bone remodeling algorithm targeting hypermineralized sites [PDF]

open access: yesMedical Engineering and Physics, Elsevier, 2020, 76, pp.56 - 68, 2021
Pharmaceutical treatments can slow bone degradation, thus reducing the fracture risk inherent in osteoporosis. Antiresorptive treatments block the over-activation of osteoclasts vs osteoblasts, but the resulting decrease in bone remodeling frequency may weaken bone structure over time, with no gain in bone volume.
arxiv   +1 more source

Thiazolidinediones and bone fractures [PDF]

open access: yesJournal of Diabetes Investigation, 2011
The topic of increased risk of bone fracture associated with thiazolidinediones (TZD) treatment first drew international attention when a higher rate of fractures in women with diabetes treated with rosiglitazone was reported in the A Diabetes Outcome Program Trial (ADOPT)1. Subsequently, a number of clinical trials and observational studies addressing
Kohei Kaku, Mitsuru Hashiramoto
openaire   +3 more sources

Cellular and molecular mediators of bone metastatic lesions [PDF]

open access: yes, 2018
Bone is the preferential site of metastasis for breast and prostate tumor. Cancer cells establish a tight relationship with the host tissue, secreting factors that stimulate or inhibit bone cells, receiving signals generated from the bone remodeling ...
Battafarano, Giulia   +3 more
core   +5 more sources

Bone mineral density and fracture risk with long-term use of inhaled corticosteroids in patients with asthma: systematic review and meta-analysis [PDF]

open access: yes, 2015
Objectives: We aimed to assess the association between long-term use of inhaled corticosteroids (ICS) and bone adverse effects in patients with asthma. Design: Systematic review and meta-analysis of fracture risk and changes in bone mineral density with ...
Agertoft   +32 more
core   +1 more source

Investigation of the cellular response to bone fractures: evidence for flexoelectricity [PDF]

open access: yesScientific Reports volume 10, Article number: 254 (2020), 2020
The recent discovery of bone flexoelectricity (electrical polarization induced by strain gradient) suggests that flexoelectricity could have physiological effects in bones, and specifically near bone fractures, where flexoelectricity is theoretically highest. Here, we report a cytological study of the interaction between crack stress and bone cells. We
arxiv   +1 more source

Gray-level co-occurrence matrix bone fracture detection [PDF]

open access: yes, 2011
Problem statement: Currently doctors in orthopedic wards inspect the bone x-ray images according to their experience and knowledge in bone fracture analysis. Manual examination of x-rays has multitude drawbacks.
Ariff, A. K.   +5 more
core   +1 more source

Effects of Risedronate in Runx2 Overexpressing Mice, an Animal Model for Evaluation of Treatment Effects on Bone Quality and Fractures [PDF]

open access: yes, 2011
Young mice overexpressing Runx2 specifically in cells of the osteoblastic lineage failed to gain bone mass and exhibited a dramatic increase in bone resorption, leading to severe osteopenia and spontaneous vertebral fractures.
A. Ostertag   +8 more
core   +3 more sources

Experimental ex-vivo validation of PMMA-based bone cements loaded with magnetic nanoparticles enabling hyperthermia of metastatic bone tumors [PDF]

open access: yes, 2017
Percutaneous vertebroplasty comprises the injection of Polymethylmethacrylate (PMMA) bone cement into vertebrae and can be used for the treatment of compression fractures of vertebrae.
Crevecoeur, Guillaume   +5 more
core   +3 more sources

Increased sclerostin associated with stress fracture of the third metacarpal bone in the Thoroughbred Racehorse [PDF]

open access: yes, 2018
Objectives: The exact aetiopathogenesis of microdamage induced long bone fractures remains unknown. These fractures are likely the result of inadequate bone remodeling in response to damage.
Henson, F, Hopper, N, Singer, E
core   +2 more sources

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