Results 161 to 170 of about 336,414 (321)

Current Advances of Antibacterial Biomaterials for Bone Regeneration

Advanced Materials Interfaces, EarlyView.
Effective treatment of infectious bone defects requires not only robust bone regeneration, but also the elimination of bacterial infection. This review highlights current cutting‐edge concepts and innovations in synthetic bone repair biomaterials and antibacterial bone repair materials, aiming to promote clinical translation and inspire broader ...
Xueping Kong, Xue Zhang, Ying Wang, Ben Zhang   +3 more
wiley   +1 more source

Progress and Application of Multifunctional Hydrogel in Radioactive Skin Injury

Advanced Materials Interfaces, EarlyView.
This review examines healing challenges in radiation‐wound injuries, where ionizing radiation impairs immune and tissue repair processes. Hydrogels, with their biocompatibility, antimicrobial properties, and drug delivery capabilities, present a transformative solution. It compares hydrogel efficacy in radiation‐induced versus common wounds, highlights
Xinyue Cui, Jingyi Wang, Xinyi Xu, Xiqian Cao, Yingtang Zhou, Jiaming Guo   +5 more
wiley   +1 more source

Clinical significance of trabecular bone score for prediction of pathologic fracture risk in patients with multiple myeloma

Osteoporosis and Sarcopenia, 2018
Objectives: Osteolytic bone lesions are common complications in multiple myeloma (MM), and can have an impact on quality of life due to the risk of fractures.
Eun Mi Lee, Bukyung Kim
doaj  

Ultra‐Flexible µ‐ECoG Arrays Based on PEDOT:PSS Micropillars

Advanced Materials Interfaces, EarlyView.
This work demonstrates an efficient procedure for fabricating ultra‐flexible neural interfaces endowed with micropatterned microelectrodes to increase surface area and characterized by extremely low impedance values to enable high‐quality recordings. The home‐built device has been shown to record somatosensory evoked potentials in vivo with exceptional
Alice Lunghi, Michele Bianchi, Pierpaolo Greco, Riccardo Viaro, Michele Di Lauro, Luciano Fadiga, Fabio Biscarini   +6 more
wiley   +1 more source

Growth Factor‐Loaded Mesoporous Silica Particles, Incorporated in Electrospun PCL Fibres, Provide Topographical and Chemical Cues for Tendon Tissue Engineering

Advanced Materials Technologies, EarlyView.
Electrospinning enables the hierarchical assembly of nanofiber‐based scaffolds for tissue engineering. However, encapsulated proteins often undergo structural changes. This study used mesoporous silica nanoparticles (MSNs) as protective carriers, mitigating protein denaturation and supporting controlled release.
Vera Citro, Marta Clerici, Matthew T. Shephard, Tina P. Dale, Aldo R. Boccaccini, Nicholas R. Forsyth   +5 more
wiley   +1 more source

A multi-stage semi-supervised learning for ankle fracture classification on CT images [PDF]

arXiv
Because of the complicated mechanism of ankle injury, it is very difficult to diagnose ankle fracture in clinic. In order to simplify the process of fracture diagnosis, an automatic diagnosis model of ankle fracture was proposed. Firstly, a tibia-fibula segmentation network is proposed for the joint tibiofibular region of the ankle joint, and the ...
arxiv  

Controlled Release of Vancomycin and Tigecycline from an Orthopaedic Implant Coating Prevents Staphylococcus aureus Infection in an Open Fracture Animal Model. [PDF]

, 2019
Introduction:Treatment of open fractures routinely involves multiple surgeries and delayed definitive fracture fixation because of concern for infection.
Bernthal, NM, Hegde, V, Loftin, AH, Niska, J, Segura, T, Stavrakis, AI, Weixian, X, Zhu, S   +7 more
core  

Hydroxyapatite Binding Peptide Lipid Nanoparticles for Biomimetic mRNA Delivery to Bone

Advanced Therapeutics, EarlyView.
Targeted delivery of therapeutic mRNA to peripheral tissues, including bone, is currently challenging. In the current work, a hydroxyapatite binding peptide (HABP) is conjugated to mRNA lipid nanoparticles (LNPs). HABP‐LNPs delivered systemically are demonstrated to reduce transfection in the liver and improve transfection in the femurs of mice ...
Joshua A. Choe, Jena E. Moseman, Jamie M. Jones, Jacobus C. Burger, Ashley M. Weichmann, Douglas G. McNeel, William L. Murphy   +6 more
wiley   +1 more source

High Dependency Unit Admissions among Patients with Lower Extremity Long Bone Fracture Visiting the Department of Orthopaedics in a Tertiary Care Centre

Journal of Nepal Medical Association
Introduction: Lower extremity long bone, femoral and tibial shaft, fractures often have associated injuries. Patients with lower extremity long bone fractures in the Department of Orthopaedics can land up in high dependency unit admissions, mostly due ...
Satish Prasad Barnawal, Bibek Banskota, Nitesh Raj Pandey, Saroj Rijal, Tarun Rajbhandari, Subhash Regmi, Ashok Kumar Banskota   +6 more
doaj   +1 more source

Insights on Advances in 3D Bioprinting for Peripheral Nerve Regeneration

Advanced Therapeutics, EarlyView.
Peripheral nerve injury is a common condition due to trauma that significantly impacts the life of the affected individual. This review explores the anatomy, classification, and pathophysiology of peripheral nerve injuries. It also discusses various types of nerve conduits and presents a detailed review of 3D bioprinted nerve conduits used in both in ...
Nasera Rizwana, Samartha M C, Ashwath Acharya, Goutam Thakur, Manasa Nune, Vipul Agarwal   +5 more
wiley   +1 more source