Results 181 to 190 of about 344,710 (298)

Cellular Adaptation to Mechanical Stress Emerges via Cell Shrinkage Triggered by Nonlinear Calcium Elevation

open access: yesAdvanced Science, EarlyView.
Here, a decision‐making mechanism underlying mechanical adaptation is demonstrated. This study demonstrates that cellular adaptation to mechanical stress can be induced by applying low‐amplitude stretch to cells. When the stretch reaches a critical amplitude threshold, it triggers Ca2⁺‐dependent positive feedback, which induces cholesterol efflux and ...
Zhengyan Wang   +21 more
wiley   +1 more source

Energy‐Efficient Fabrication of Biomimetic Materials for Sustainable Infrastructure Applications

open access: yesAdvanced Science, EarlyView.
Inspired by nacre's “brick‐and‐mortar” structure, this work develops an energy‐efficient approach that utilizes ice‐templating technology as the structure framework and carbon mineralization for rapid CaCO3 production, resulting in a strong yet tough carbon mineralized material (CMM) under mild conditions while also fixing CO2.
Jingze Chen   +4 more
wiley   +1 more source

A Novel Cranial Bone Transport Technique Repairs Skull Defect and Minimizes Brain Injury Outcome in Traumatic Brain Injury Rats

open access: yesAdvanced Science, EarlyView.
This study introduces a novel, safe, and effective surgical technique: Cranial bone transport (CBT) to improve traumatic brain injury (TBI) outcomes in rats. CBT significantly accelerated skull defect bone repair in addition to its promoting effects on neurological function recovery. This work provides an alternative therapy for patients suffering from
Shanshan Bai   +20 more
wiley   +1 more source

Targeting Hyperglycemic Bone Pre‐Metastatic Niche for Breast Cancer Bone Metastasis Therapy

open access: yesAdvanced Science, EarlyView.
This study reveals that breast cancer creates a hyperglycemic pre‐metastatic niche in bone prior to colonization and amplifies glucose metabolism post‐metastasis. To target this mechanism, a biomimetic enzyme‐engineered nanoplatform that disrupts tumor glycolytic pathways, proposing a therapeutic strategy to inhibit breast cancer bone metastasis by ...
Jianxin Ye   +13 more
wiley   +1 more source

Stretchable and Biodegradable Thermally Expandable Composites with Microfluidics for On‐Demand and Programmable Destruction of Electronics

open access: yesAdvanced Science, EarlyView.
Soft, stretchable, thermally expandable composites that enable tunable, mechanically driven, on‐demand destruction of transient electronics are developed. Integrated with microfluidics and wireless circuits, the composites facilitate precise, selective device collapse and frequency‐controlled drug release, highlighting the broad potential in ...
Chan‐Hwi Eom   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy